U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

UBC4 ubiquitin conjugating enzyme 4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 834136, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
UBC4
Official Full Name
ubiquitin conjugating enzyme 4
Primary source
TAIR:AT5G41340
Locus tag
AT5G41340
See related
Araport:AT5G41340
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATUBC4; MYC6.5; MYC6_5; ubiquitin conjugating enzyme 4; UBIQUITIN CONJUGATING ENZYME 4
Summary
Belongs to Ubiquitin conjugating enzyme family. Gene expression is developmentally regulated.
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See UBC4 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
6
Sequence:
Chromosome: 5; NC_003076.8 (16538063..16540189, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene stress response NST1-like protein Neighboring gene ncRNA Neighboring gene BTB/POZ domain with WD40/YVTN repeat-like protein Neighboring gene RING/U-box superfamily protein Neighboring gene homolog of Xeroderma pigmentosum complementation group B 2

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Members of two gene families encoding ubiquitin-conjugating enzymes, AtUBC1-3 and AtUBC4-6, from Arabidopsis thaliana are differentially expressed. Thoma S, et al. Plant Mol Biol, 1996 Jun. PMID 8790283
  2. Homologues of wheat ubiquitin-conjugating enzymes--TaUBC1 and TaUBC4 are encoded by small multigene families in Arabidopsis thaliana. Sullivan ML, et al. Plant Mol Biol, 1994 Feb. PMID 8155884
  3. Arabidopsis Ubiquitin-Conjugating Enzymes UBC4, UBC5, and UBC6 Have Major Functions in Sugar Metabolism and Leaf Senescence. Wang S, et al. Int J Mol Sci, 2022 Sep 22. PMID 36232444, Free PMC Article
  4. Effect of Arabidopsis COP10 ubiquitin E2 enhancement activity across E2 families and functional conservation among its canonical homologues. Lau OS, et al. Biochem J, 2009 Mar 15. PMID 19061479
  5. Genome analysis and functional characterization of the E2 and RING-type E3 ligase ubiquitination enzymes of Arabidopsis. Kraft E, et al. Plant Physiol, 2005 Dec. PMID 16339806, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Arabidopsis Ubiquitin-Conjugating Enzymes UBC4, UBC5, and UBC6 Have Major Functions in Sugar Metabolism and Leaf Senescence.
    Title: Arabidopsis Ubiquitin-Conjugating Enzymes UBC4, UBC5, and UBC6 Have Major Functions in Sugar Metabolism and Leaf Senescence.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help
NM_001344399.1
NM_123499.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ubiquitin conjugating enzyme activity IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin-protein transferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ubiquitin-protein transferase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
  
NOT involved_in response to heat IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within ubiquitin-dependent protein catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within ubiquitin-dependent protein catabolic process TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
NOT located_in cytosol RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

Go to the top of the page Help
Preferred Names
ubiquitin conjugating enzyme 4
NP_568589.1
  • ubiquitin conjugating enzyme 4 (UBC4); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608), Ubiquitin-conjugating enzyme (InterPro:IPR015581); BEST Arabidopsis thaliana protein match is: ubiquitin-conjugating enzyme 5 (TAIR:AT1G63800.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    16538063..16540189 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_123499.5 → NP_568589.1  ubiquitin conjugating enzyme 4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_568589.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P42748, Q4TZ05, Q9FN66
    UniProtKB/TrEMBL
    A0A5S9YAA3, A0A654G6Z0
    Conserved Domains (1) summary
    pfam00179
    Location:7 → 143
    UQ_con; Ubiquitin-conjugating enzyme

  2. NM_001344399.1 → NP_001331159.1  ubiquitin conjugating enzyme 4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BD13
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P42748.2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.