U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

UVH1 Restriction endonuclease, type II-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 834117, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
UVH1
Official Full Name
Restriction endonuclease, type II-like superfamily protein
Primary source
TAIR:AT5G41150
Locus tag
AT5G41150
See related
Araport:AT5G41150
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATRAD1; MEE6.22; MEE6_22; RAD1; REPAIR ENDONUCLEASE; ULTRAVIOLET HYPERSENSITIVE 1
Summary
Confers resistance to UV radiation. Homolog of the human xeroderma pigmentosum group F DNA repair and yeast Rad1 proteins
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See UVH1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
9
Sequence:
Chromosome: 5; NC_003076.8 (16472764..16477417, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene meiosis chromosome segregation family protein Neighboring gene Esterase/lipase/thioesterase family protein Neighboring gene Esterase/lipase/thioesterase family protein Neighboring gene Myosin heavy chain-related protein Neighboring gene Pentatricopeptide repeat (PPR-like) superfamily protein Neighboring gene purine permease 12 Neighboring gene leucine-rich repeat transmembrane protein kinase family protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Role of the AtRad1p endonuclease in homologous recombination in plants. Dubest S, et al. EMBO Rep, 2002 Nov. PMID 12393748, Free PMC Article
  2. Repair of damaged DNA by Arabidopsis cell extract. Li A, et al. Plant Cell, 2002 Jan. PMID 11826311, Free PMC Article
  3. The Arabidopsis UVH1 gene is a homolog of the yeast repair endonuclease RAD1. Fidantsef AL, et al. Plant Physiol, 2000 Oct. PMID 11027708, Free PMC Article
  4. Repair of UV damage in plants by nucleotide excision repair: Arabidopsis UVH1 DNA repair gene is a homolog of Saccharomyces cerevisiae Rad1. Liu Z, et al. Plant J, 2000 Mar. PMID 10758502
  5. ERCC1/XPF protects short telomeres from homologous recombination in Arabidopsis thaliana. Vannier JB, et al. PLoS Genet, 2009 Feb. PMID 19214203, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ERCC1 and XPF protect short telomeres from homologous recombination.
    Title: ERCC1/XPF protects short telomeres from homologous recombination in Arabidopsis thaliana.
Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Homology

NM_001036914.1
NM_001344387.1
NM_001344388.1
NM_123480.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables single-stranded DNA endodeoxyribonuclease activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA repair IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within double-strand break repair via homologous recombination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within nucleotide-excision repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within pyrimidine dimer repair by nucleotide-excision repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in pyrimidine dimer repair by nucleotide-excision repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to oxidative stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to radiation IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Restriction endonuclease, type II-like superfamily protein
NP_001031991.1
  • ULTRAVIOLET HYPERSENSITIVE 1 (UVH1); Has 503 Blast hits to 463 proteins in 204 species: Archae - 16; Bacteria - 0; Metazoa - 188; Fungi - 168; Plants - 53; Viruses - 0; Other Eukaryotes - 78 (source: NCBI BLink).
NP_198931.1
  • ULTRAVIOLET HYPERSENSITIVE 1 (UVH1); CONTAINS InterPro DOMAIN/s: ERCC4 domain (InterPro:IPR006166), Restriction endonuclease, type II-like (InterPro:IPR011335), DNA repair nuclease, XPF-type/Helicase (InterPro:IPR020819); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    16472764..16477417 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_123480.4 → NP_198931.1  Restriction endonuclease, type II-like superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_198931.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9LKI5, Q9SE36, Q9SPL7
    UniProtKB/TrEMBL
    A0A178UNJ5, A0A5S9Y9X6, Q2F6I1
    Conserved Domains (1) summary
    TIGR00596
    Location:87 → 948
    rad1; DNA repair protein (rad1)

  2. NM_001344387.1 → NP_001330263.1  Restriction endonuclease, type II-like superfamily protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UNJ5, A0A1P8BAA2

  3. NM_001344388.1 → NP_001330264.1  Restriction endonuclease, type II-like superfamily protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4JWY5

  4. NM_001036914.1 → NP_001031991.1  Restriction endonuclease, type II-like superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001031991.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4JWY5
    Conserved Domains (1) summary
    TIGR00596
    Location:87 → 689
    rad1; DNA repair protein (rad1)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LKI5.2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.