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GLIP1 GDSL lipase 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 834101, updated on 18-Sep-2024

Summary

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Official Symbol
GLIP1
Official Full Name
GDSL lipase 1
Primary source
TAIR:AT5G40990
Locus tag
AT5G40990
See related
Araport:AT5G40990
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
GDSL lipase 1; MEE6.6; MEE6_6
Summary
Component of plant resistance. Contains lipase signature motif and GDSL domain. Directly interferes with the fungal infection process by acting on fungal cell walls through its action as a antimicrobial compound. Critical component for both local and systemic resistance responses in the incompatible interaction with Alternaria brassicicola in the ethylene-dependent pathway.
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Genomic context

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See GLIP1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
5
Sequence:
Chromosome: 5; NC_003076.8 (16418842..16420616)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene hypothetical protein (DUF 3339) Neighboring gene AT.I.24-6 protein, putative (DUF 3339) Neighboring gene uncharacterized protein Neighboring gene YELLOW STRIPE like 4 Neighboring gene ncRNA Neighboring gene DNA directed RNA polymerase, 7 kDa subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. GDSL lipase 1 regulates ethylene signaling and ethylene-associated systemic immunity in Arabidopsis. Kim HG, et al. FEBS Lett, 2014 May 2. PMID 24631536
  2. GDSL LIPASE1 modulates plant immunity through feedback regulation of ethylene signaling. Kim HG, et al. Plant Physiol, 2013 Dec. PMID 24170202, Free PMC Article
  3. GDSL lipase-like 1 regulates systemic resistance associated with ethylene signaling in Arabidopsis. Kwon SJ, et al. Plant J, 2009 Apr. PMID 19077166
  4. Secretome analysis reveals an Arabidopsis lipase involved in defense against Alternaria brassicicola. Oh IS, et al. Plant Cell, 2005 Oct. PMID 16126835, Free PMC Article
  5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. GLIP1 regulates the fine-tuning of ethylene signaling and ethylene-salicylic acid cross talk.
    Title: GDSL LIPASE1 modulates plant immunity through feedback regulation of ethylene signaling.
  2. GLIP1 positively and negatively regulates ethylene signaling, resulting in an ethylene-associated, necrotroph-induced immune response.
    Title: GDSL lipase 1 regulates ethylene signaling and ethylene-associated systemic immunity in Arabidopsis.
  3. GLIP1-mediated pathogen resistance is dependent on ethylene signaling.
    Title: GDSL lipase-like 1 regulates systemic resistance associated with ethylene signaling in Arabidopsis.
  4. GDSL LIPASE1 (GLIP1), in association with ethylene signaling, may be a critical component in plant resistance to necrotrophic fungus Alternaria brassicicola.[GLIP1]
    Title: Secretome analysis reveals an Arabidopsis lipase involved in defense against Alternaria brassicicola.
Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables lipase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables lipase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within defense response to bacterium IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within defense response to fungus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in defense response to fungus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within induced systemic resistance, ethylene mediated signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in jasmonic acid and ethylene-dependent systemic resistance, ethylene mediated signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to fungus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to salicylic acid IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in systemic acquired resistance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in extracellular space IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
GDSL lipase 1
NP_198915.1
  • GDSL lipase 1 (GLIP1); CONTAINS InterPro DOMAIN/s: Lipase, GDSL, active site (InterPro:IPR008265), Lipase, GDSL (InterPro:IPR001087); BEST Arabidopsis thaliana protein match is: GDSL-motif lipase 2 (TAIR:AT1G53940.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    16418842..16420616
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_123464.2 → NP_198915.1  GDSL lipase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_198915.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9FLN0
    UniProtKB/TrEMBL
    A0A654G700
    Conserved Domains (1) summary
    cd01837
    Location:37 → 358
    SGNH_plant_lipase_like; SGNH_plant_lipase_like, a plant specific subfamily of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9FLN0.1

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