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SDH2-2 succinate dehydrogenase 2-2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 834065, updated on 18-Sep-2024

Summary

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Official Symbol
SDH2-2
Official Full Name
succinate dehydrogenase 2-2
Primary source
TAIR:AT5G40650
Locus tag
AT5G40650
See related
Araport:AT5G40650
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
MNF13.170; MNF13_170; succinate dehydrogenase 2-2
Summary
One of three isoforms of the iron-sulfur component of the succinate dehydrogenase complex, a component of the mitochondrial respiratory chain complex II. The product of the nuclear encoded gene is imported into the mitochondrion. Expressed during germination and post-germinative growth.
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Genomic context

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See SDH2-2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
2
Sequence:
Chromosome: 5; NC_003076.8 (16281394..16283527)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Ubiquitin-like superfamily protein Neighboring gene uncharacterized protein Neighboring gene RPM1-interacting protein 4 (RIN4) family protein Neighboring gene ATP12 protein-like protein Neighboring gene PQ-loop repeat family protein / transmembrane family protein Neighboring gene Galactose oxidase/kelch repeat superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nuclear SDH2-1 and SDH2-2 genes, encoding the iron-sulfur subunit of mitochondrial complex II in Arabidopsis, have distinct cell-specific expression patterns and promoter activities. Elorza A, et al. Plant Physiol, 2004 Dec. PMID 15563621, Free PMC Article
  2. A nuclear gene for the iron-sulfur subunit of mitochondrial complex II is specifically expressed during Arabidopsis seed development and germination. Elorza A, et al. Plant Cell Physiol, 2006 Jan. PMID 16249327
  3. Three different genes encode the iron-sulfur subunit of succinate dehydrogenase in Arabidopsis thaliana. Figueroa P, et al. Plant Mol Biol, 2001 May. PMID 11442063
  4. Mitochondrial cytochrome c oxidase and succinate dehydrogenase complexes contain plant specific subunits. Millar AH, et al. Plant Mol Biol, 2004 Sep. PMID 15604729
  5. Functional and composition differences between mitochondrial complex II in Arabidopsis and rice are correlated with the complex genetic history of the enzyme. Huang S, et al. Plant Mol Biol, 2010 Feb. PMID 19924544

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. An analysis of the expression of SDH2-1, SDH2-2, and SDH2-3 (not detected) in A. thaliana, including differential expression in plant organs.
    Title: Nuclear SDH2-1 and SDH2-2 genes, encoding the iron-sulfur subunit of mitochondrial complex II in Arabidopsis, have distinct cell-specific expression patterns and promoter activities.
  2. during germination the embryo-specific SDH2-3 is replaced by SDH2-1 or SDH2-2 in mitochondrial complex II
    Title: A nuclear gene for the iron-sulfur subunit of mitochondrial complex II is specifically expressed during Arabidopsis seed development and germination.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001344348.1
NM_123430.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables electron transfer activity IEA
Inferred from Electronic Annotation
more info
  
enables electron transfer activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables succinate dehydrogenase (quinone) activity IEA
Inferred from Electronic Annotation
more info
  
enables succinate dehydrogenase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables zinc ion binding HDA PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within mitochondrial electron transport, succinate to ubiquinone ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  
located_in plastid HDA PubMed 
part_of respiratory chain complex II (succinate dehydrogenase) IDA
Inferred from Direct Assay
more info
 PubMed 
part_of respiratory chain complex II (succinate dehydrogenase) ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
succinate dehydrogenase 2-2
NP_198881.1
  • succinate dehydrogenase 2-2 (SDH2-2); CONTAINS InterPro DOMAIN/s: Ferredoxin (InterPro:IPR001041), Beta-grasp fold, ferredoxin-type (InterPro:IPR012675), Fumarate reductase, C-terminal (InterPro:IPR012285), 2Fe-2S ferredoxin, iron-sulphur binding site (InterPro:IPR006058), 4Fe-4S ferredoxin, iron-sulpur binding domain (InterPro:IPR017896), 4Fe-4S ferredoxin, iron-sulphur binding, conserved site (InterPro:IPR017900), Alpha-helical ferredoxin (InterPro:IPR009051), Succinate dehydrogenase/fumarate reductase iron-sulphur protein (InterPro:IPR004489); BEST Arabidopsis thaliana protein match is: succinate dehydrogenase 2-1 (TAIR:AT3G27380.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    16281394..16283527
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_123430.2 → NP_198881.1  succinate dehydrogenase 2-2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_198881.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8LB02, Q9FM32, Q9G3L9
    UniProtKB/TrEMBL
    A0A178UNP1, A0A5S9YC30
    Conserved Domains (1) summary
    PLN00129
    Location:1 → 280
    PLN00129; succinate dehydrogenase [ubiquinone] iron-sulfur subunit

  2. NM_001344348.1 → NP_001332094.1  succinate dehydrogenase 2-2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UNP1, A0A1P8BFU4
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8LB02.2

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