U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Methylenetetrahydrofolate reductase family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 833862, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Full Name
Methylenetetrahydrofolate reductase family protein
Primary source
TAIR:AT5G38710
Locus tag
AT5G38710
See related
Araport:AT5G38710
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
MKD10.10; MKD10_10
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 5
Exon count:
4
Sequence:
Chromosome: 5; NC_003076.8 (15501126..15504269)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene cotton fiber protein Neighboring gene pseudo Neighboring gene miscRNA Neighboring gene ribosomal RNA-processing 7 protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Non-redundant functions of two proline dehydrogenase isoforms in Arabidopsis. Funck D, et al. BMC Plant Biol, 2010 Apr 19. PMID 20403182, Free PMC Article
  2. Differential control and function of Arabidopsis ProDH1 and ProDH2 genes on infection with biotrophic and necrotrophic pathogens. Rizzi YS, et al. Mol Plant Pathol, 2017 Oct. PMID 27526663, Free PMC Article
  3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ProDH1 and ProDH2 are both necessary to achieve maximum resistance against Pseudomonas syringae pv. tomato AvrRpm1 and B. cinerea.[ProDH2]
    Title: Differential control and function of Arabidopsis ProDH1 and ProDH2 genes on infection with biotrophic and necrotrophic pathogens.
  2. ProDH2 may play an important role in Proline homeostasis in the vasculature, especially under stress conditions that promote Proline accumulation. [ProDH2]
    Title: Non-redundant functions of two proline dehydrogenase isoforms in Arabidopsis.
Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help
NM_001344262.1
NM_123232.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables proline dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
enables proline dehydrogenase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in proline catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in proline catabolic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in proline catabolic process to glutamate IEA
Inferred from Electronic Annotation
more info
  
involved_in response to osmotic stress IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in response to water deprivation IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Methylenetetrahydrofolate reductase family protein
NP_198687.1
  • Methylenetetrahydrofolate reductase family protein; FUNCTIONS IN: proline dehydrogenase activity; INVOLVED IN: oxidation reduction, proline catabolic process, glutamate biosynthetic process; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Proline dehydrogenase (InterPro:IPR002872), Proline oxidase (InterPro:IPR015659); BEST Arabidopsis thaliana protein match is: Methylenetetrahydrofolate reductase family protein (TAIR:AT3G30775.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    15501126..15504269
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_123232.3 → NP_198687.1  Methylenetetrahydrofolate reductase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_198687.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q6NKX1, Q9FKR5
    UniProtKB/TrEMBL
    A0A178UQV1
    Conserved Domains (2) summary
    PLN02681
    Location:19 → 476
    PLN02681; proline dehydrogenase
    pfam01619
    Location:226 → 456
    Pro_dh; Proline dehydrogenase

  2. NM_001344262.1 → NP_001330954.1  Methylenetetrahydrofolate reductase family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UQV1, A0A1P8BCG0
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6NKX1.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools