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ASF1B anti- silencing function 1b [ Arabidopsis thaliana (thale cress) ]

Gene ID: 833791, updated on 18-Sep-2024

Summary

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Official Symbol
ASF1B
Official Full Name
anti- silencing function 1b
Primary source
TAIR:AT5G38110
Locus tag
AT5G38110
See related
Araport:AT5G38110
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
anti- silencing function 1b; F16F17.110; F16F17_110; SGA01; SGA1
Summary
This gene is predicted to encode a silencing group A protein. Plant lines expressing RNAi constructs directed against SGA1 have reduced levels of agrobacterium-mediated root transformation. Its expression is regulated during cell cycle progression through E2F transcription factors.
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Genomic context

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See ASF1B in Genome Data Viewer
Location:
chromosome: 5
Exon count:
3
Sequence:
Chromosome: 5; NC_003076.8 (15208358..15210335)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene ncRNA Neighboring gene AMP-dependent synthetase and ligase family protein Neighboring gene HXXXD-type acyl-transferase family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Histone chaperone ASF1 is involved in gene transcription activation in response to heat stress in Arabidopsis thaliana. Weng M, et al. Plant Cell Environ, 2014 Sep. PMID 24548003
  2. ANTI-SILENCING FUNCTION1 proteins are involved in ultraviolet-induced DNA damage repair and are cell cycle regulated by E2F transcription factors in Arabidopsis. Lario LD, et al. Plant Physiol, 2013 Jun. PMID 23596192, Free PMC Article
  3. Arabidopsis homologues of the histone chaperone ASF1 are crucial for chromatin replication and cell proliferation in plant development. Zhu Y, et al. Plant J, 2011 May. PMID 21251110
  4. TOUSLED kinase activity oscillates during the cell cycle and interacts with chromatin regulators. Ehsan H, et al. Plant Physiol, 2004 Apr. PMID 15047893, Free PMC Article
  5. RNAi-mediated gene silencing reveals involvement of Arabidopsis chromatin-related genes in Agrobacterium-mediated root transformation. Crane YM, et al. Proc Natl Acad Sci U S A, 2007 Sep 18. PMID 17827277, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. This study unravels an important function of AtASF1A/B in plant heat stress response.
    Title: Histone chaperone ASF1 is involved in gene transcription activation in response to heat stress in Arabidopsis thaliana.
  2. ASF1A and ASF1B are regulated by cell cycle progression and are involved in DNA repair after UV-B irradiation.
    Title: ANTI-SILENCING FUNCTION1 proteins are involved in ultraviolet-induced DNA damage repair and are cell cycle regulated by E2F transcription factors in Arabidopsis.
  3. AtASF1A and AtASF1B proteins bind the histone H3. Simultaneous knockdown impairs chromatin replication and perturbs genome stability and function, causing S-phase and DNA repair checkpoint activation, and abnormal plant growth and development.
    Title: Arabidopsis homologues of the histone chaperone ASF1 are crucial for chromatin replication and cell proliferation in plant development.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_123171.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA-mediated transformation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within cell division IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within double-strand break repair via homologous recombination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within mitotic cell size control checkpoint signaling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of cell size IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within trichome branching IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
anti- silencing function 1b
NP_198627.1
  • anti- silencing function 1b (ASF1B); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: DNA mediated transformation, nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; LOCATED IN: nucleus; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Histone chaperone, ASF1-like (InterPro:IPR006818); BEST Arabidopsis thaliana protein match is: ASF1 like histone chaperone (TAIR:AT1G66740.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    15208358..15210335
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_123171.4 → NP_198627.1  anti- silencing function 1b [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_198627.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9LS09
    UniProtKB/TrEMBL
    A0A178UQ02, A0A5S9Y9C1, A0A654G5W7
    Conserved Domains (1) summary
    pfam04729
    Location:1 → 154
    ASF1_hist_chap; ASF1 like histone chaperone
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LS09.1

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