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ENHANCED DISEASE RESISTANCE protein (DUF1336) [ Arabidopsis thaliana (thale cress) ]

Gene ID: 833472, updated on 18-Sep-2024

Summary

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Official Full Name
ENHANCED DISEASE RESISTANCE protein (DUF1336)
Primary source
TAIR:AT5G35180
Locus tag
AT5G35180
See related
Araport:AT5G35180
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
T25C13.60; T25C13_60
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Genomic context

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Location:
chromosome: 5
Exon count:
26
Sequence:
Chromosome: 5; NC_003076.8 (13424316..13433067)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Endomembrane protein 70 protein family Neighboring gene adenylate kinase family protein Neighboring gene proline-rich extensin-like family protein Neighboring gene Defensin-like (DEFL) family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Learning the lipid language of plant signalling. van Leeuwen W, et al. Trends Plant Sci, 2004 Aug. PMID 15358268
  2. Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism. Ito J, et al. J Proteome Res, 2011 Apr 1. PMID 21166475
  3. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
  4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

General gene information

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Homology

NM_001125838.2
NM_001125839.2
NM_001161275.1
NM_122909.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables lipid binding IEA
Inferred from Electronic Annotation
more info
  
enables phosphatidylinositol binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within signal transduction ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
NOT located_in cytosol RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  
located_in plastid HDA PubMed 

General protein information

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Preferred Names
ENHANCED DISEASE RESISTANCE protein (DUF1336)
NP_001119310.1
  • FUNCTIONS IN: phosphoinositide binding; INVOLVED IN: signal transduction; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1336 (InterPro:IPR009769), Lipid-binding START (InterPro:IPR002913), Pleckstrin homology (InterPro:IPR001849); BEST Arabidopsis thaliana protein match is: ENHANCED DISEASE RESISTANCE 2 (TAIR:AT4G19040.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_001119311.1
  • FUNCTIONS IN: phosphoinositide binding; INVOLVED IN: signal transduction; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Lipid-binding START (InterPro:IPR002913), Pleckstrin homology (InterPro:IPR001849); BEST Arabidopsis thaliana protein match is: Pleckstrin homology (PH) domain-containing protein / lipid-binding START domain-containing protein (TAIR:AT5G45560.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_001154747.1
  • FUNCTIONS IN: phosphoinositide binding; INVOLVED IN: signal transduction; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1336 (InterPro:IPR009769), Lipid-binding START (InterPro:IPR002913); BEST Arabidopsis thaliana protein match is: ENHANCED DISEASE RESISTANCE 2 (TAIR:AT4G19040.1); Has 454 Blast hits to 426 proteins in 37 species: Archae - 0; Bacteria - 0; Metazoa - 1; Fungi - 2; Plants - 378; Viruses - 2; Other Eukaryotes - 71 (source: NCBI BLink).
NP_568526.1
  • FUNCTIONS IN: phosphoinositide binding; INVOLVED IN: signal transduction; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1336 (InterPro:IPR009769), Lipid-binding START (InterPro:IPR002913), Pleckstrin homology (InterPro:IPR001849); BEST Arabidopsis thaliana protein match is: ENHANCED DISEASE RESISTANCE 2 (TAIR:AT4G19040.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    13424316..13433067
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001344098.1 → NP_001332513.1  ENHANCED DISEASE RESISTANCE protein (DUF1336) [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UKI1, A0A1P8BH65

  2. NM_122909.3 → NP_568526.1  ENHANCED DISEASE RESISTANCE protein (DUF1336) [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_568526.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UKI1, A0A5S9Y8L4, Q8W553
    Conserved Domains (1) summary
    PLN00188
    Location:60 → 774
    PLN00188; enhanced disease resistance protein (EDR2); Provisional

  3. NM_001125838.2 → NP_001119310.1  ENHANCED DISEASE RESISTANCE protein (DUF1336) [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001119310.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UL44, B3H5W6
    Conserved Domains (3) summary
    cd00177
    Location:238 → 437
    START; Lipid-binding START domain of mammalian STARD1-STARD15 and related proteins
    PLN00188
    Location:60 → 774
    PLN00188; enhanced disease resistance protein (EDR2); Provisional
    pfam07059
    Location:563 → 768
    DUF1336; Protein of unknown function (DUF1336)

  4. NM_001161275.1 → NP_001154747.1  ENHANCED DISEASE RESISTANCE protein (DUF1336) [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001154747.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UKI1, F4JYC1
    Conserved Domains (3) summary
    cd00177
    Location:238 → 470
    START; Lipid-binding START domain of mammalian STARD1-STARD15 and related proteins
    PLN00188
    Location:60 → 807
    PLN00188; enhanced disease resistance protein (EDR2); Provisional
    pfam07059
    Location:596 → 801
    DUF1336; Protein of unknown function (DUF1336)

  5. NM_001125839.2 → NP_001119311.1  ENHANCED DISEASE RESISTANCE protein (DUF1336) [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001119311.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B3H745
    Conserved Domains (3) summary
    cd00177
    Location:238 → 437
    START; Lipid-binding START domain of mammalian STARD1-STARD15 and related proteins
    PLN00188
    Location:60 → 585
    PLN00188; enhanced disease resistance protein (EDR2); Provisional
    pfam07059
    Location:563 → 586
    DUF1336; Protein of unknown function (DUF1336)
Nucleotide Protein
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