arogenate dehydrogenase [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Full Name: arogenate dehydrogenase
Primary source: TAIR:AT5G34930
Locus tag: AT5G34930
See related: Araport:AT5G34930
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: T2L5.1
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Genomic context

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See in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 2

Sequence:: Chromosome: 5; NC_003076.8 (13233357..13235763)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These results revealed that TyrA1 and TyrA2 have distinct and overlapping functions in flower and leaf development, respectively, and that imbalance of tyrosine, caused by altered TyrA activity and regulation, impacts growth and development of Arabidopsis. [TyrA1]
Title: Imbalance of tyrosine by modulating TyrA arogenate dehydrogenases impacts growth and development of Arabidopsis thaliana.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001344091.1

Supported by ESTs:

NM_122884.2

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables NAD+ binding	IEA Inferred from Electronic Annotation more info
enables arogenate dehydrogenase (NADP+) activity	IDA Inferred from Direct Assay more info	PubMed
enables arogenate dehydrogenase (NADP+) activity	IEA Inferred from Electronic Annotation more info
enables prephenate dehydrogenase (NADP+) activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in tyrosine biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in tyrosine metabolic process	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: arogenate dehydrogenase

NP_198343.1

arogenate dehydrogenase; FUNCTIONS IN: binding, prephenate dehydrogenase (NADP+) activity, catalytic activity; INVOLVED IN: tyrosine biosynthetic process, metabolic process; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Prephenate dehydrogenase (InterPro:IPR003099), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: prephenate dehydrogenase family protein (TAIR:AT1G15710.1); Has 1942 Blast hits to 1528 proteins in 619 species: Archae - 162; Bacteria - 1128; Metazoa - 21; Fungi - 62; Plants - 205; Viruses - 0; Other Eukaryotes - 364 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

13233357..13235763

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001344090.1 → NP_001331736.1 arogenate dehydrogenase [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8BET1, A0A5S9Y860

Conserved Domains (1) summary

PLN02712
Location:25 → 662

PLN02712; arogenate dehydrogenase
NM_122884.2 → NP_198343.1 arogenate dehydrogenase [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_198343.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O82603, Q944B6

UniProtKB/TrEMBL

A0A654G549

Conserved Domains (1) summary

PLN02712
Location:1 → 640

PLN02712; arogenate dehydrogenase
NM_001344091.1 → NP_001331735.1 arogenate dehydrogenase [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8BET3, A0A654G549