U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CYCA2;1 cyclin a2;1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 832610, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
CYCA2;1
Official Full Name
cyclin a2;1
Primary source
TAIR:AT5G25380
Locus tag
AT5G25380
See related
Araport:AT5G25380
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
cyclin a2;1; F18G18.15; F18G18_15
Summary
core cell cycle genes
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CYCA2;1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
11
Sequence:
Chromosome: 5; NC_003076.8 (8814517..8817887)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene phospholipase D alpha 3 Neighboring gene Integrase-type DNA-binding superfamily protein Neighboring gene Nucleotide-sugar transporter family protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. SAMBA, a plant-specific anaphase-promoting complex/cyclosome regulator is involved in early development and A-type cyclin stabilization. Eloy NB, et al. Proc Natl Acad Sci U S A, 2012 Aug 21. PMID 22869741, Free PMC Article
  2. Transcriptional control of early vein expression of CYCA2; 1 and CYCA2;4 in Arabidopsis leaves. Donner TJ, et al. Mech Dev, 2013 Jan. PMID 22842098
  3. Increased level of polyploidy1, a conserved repressor of CYCLINA2 transcription, controls endoreduplication in Arabidopsis. Yoshizumi T, et al. Plant Cell, 2006 Oct. PMID 17012601, Free PMC Article
  4. Developmental regulation of CYCA2s contributes to tissue-specific proliferation in Arabidopsis. Vanneste S, et al. EMBO J, 2011 Jul 19. PMID 21772250, Free PMC Article
  5. Functional modules in the Arabidopsis core cell cycle binary protein-protein interaction network. Boruc J, et al. Plant Cell, 2010 Apr. PMID 20407024, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. We show that stage-specific expression of CYCA2;1 and CYCA2;4 in vein development depends on regulatory elements containing, respectively, one and three evolutionarily conserved transcription-factor binding sites
    Title: Transcriptional control of early vein expression of CYCA2; 1 and CYCA2;4 in Arabidopsis leaves.
  2. SAMBA regulates cell proliferation during early development by targeting CYCLIN A2 for APC/C-mediated proteolysis
    Title: SAMBA, a plant-specific anaphase-promoting complex/cyclosome regulator is involved in early development and A-type cyclin stabilization.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help
NM_001343923.1
NM_001343925.1
NM_122447.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase regulator activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA endoreduplication IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitotic cell cycle phase transition IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within mitotic prophase IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within phloem or xylem histogenesis IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

Go to the top of the page Help
Preferred Names
cyclin a2;1
NP_001318646.1
  • cyclin a2;1 (CYCA2;1); FUNCTIONS IN: cyclin-dependent protein kinase regulator activity; INVOLVED IN: regulation of cell cycle, DNA endoreduplication; LOCATED IN: nucleus, chloroplast; EXPRESSED IN: 11 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: G2/mitotic-specific cyclin A (InterPro:IPR015453), Cyclin, C-terminal (InterPro:IPR004367), Cyclin-like (InterPro:IPR011028), Cyclin-related (InterPro:IPR013763), Cyclin, N-terminal (InterPro:IPR006671), Cyclin, A/B/D/E (InterPro:IPR014400), Cyclin (InterPro:IPR006670); BEST Arabidopsis thaliana protein match is: mitotic-like cyclin 3B from Arabidopsis (TAIR:AT5G11300.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    8814517..8817887
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001343924.1 → NP_001332474.1  cyclin a2;1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BH20, A0A654G4U3

  2. NM_001343923.1 → NP_001318646.1  cyclin a2;1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BH26, A0A654G4U3

  3. NM_122447.3 → NP_197920.2  cyclin a2;1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_197920.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BH26, A0A654G4U3
    Conserved Domains (2) summary
    pfam00134
    Location:177 → 303
    Cyclin_N; Cyclin, N-terminal domain
    pfam02984
    Location:305 → 428
    Cyclin_C; Cyclin, C-terminal domain

  4. NM_001343925.1 → NP_001332473.1  cyclin a2;1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F4JWR7, Q39071, Q9ZU09
    UniProtKB/TrEMBL
    A0A654G4U3
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q39071.3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.