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PLDALPHA3 phospholipase D alpha 3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 832609, updated on 18-Sep-2024

Summary

Official Symbol
PLDALPHA3
Official Full Name
phospholipase D alpha 3
Primary source
TAIR:AT5G25370
Locus tag
AT5G25370
See related
Araport:AT5G25370
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F18G18.110; F18G18_110; phospholipase D alpha 3
Summary
member of C2-PLD subfamily. Analyses on the gene structures/sequences, overall amino acid sequences, and domain structures indicate that PLDalpha3 is most closely related to other two PLDalphas than to other PLDs. Phylogenetic analysis has not identified a true ortholog for PLDalpha3. Involved in hyperosmotic response.
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Genomic context

See PLDALPHA3 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
5
Sequence:
Chromosome: 5; NC_003076.8 (8803829..8807783, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene EIN3-binding F box protein 2 Neighboring gene uncharacterized protein Neighboring gene cyclin a2;1 Neighboring gene Integrase-type DNA-binding superfamily protein

Pathways from PubChem

General gene information

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables N-acylphosphatidylethanolamine-specific phospholipase D activity  
enables calcium ion binding  
enables phospholipase D activity PubMed 
enables phospholipase D activity  
enables phospholipase D activity  
Component Evidence Code Pubs
located_in membrane  

General protein information

Preferred Names
phospholipase D alpha 3
NP_001318645.1
  • phospholipase D alpha 3 (PLDALPHA3); FUNCTIONS IN: phospholipase D activity; INVOLVED IN: response to water deprivation, response to salt stress, response to abscisic acid stimulus, membrane lipid catabolic process; LOCATED IN: membrane; EXPRESSED IN: leaf apex, root, flower; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), Phospholipase D (InterPro:IPR015679), Phospholipase D, plant (InterPro:IPR011402), Phospholipase D/Transphosphatidylase (InterPro:IPR001736), C2 calcium-dependent membrane targeting (InterPro:IPR000008); BEST Arabidopsis thaliana protein match is: phospholipase D alpha 1 (TAIR:AT3G15730.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    8803829..8807783 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001343921.1 → NP_001331647.1  phospholipase D alpha 3 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P58766
    UniProtKB/TrEMBL
    A0A654G4K6
  2. NM_122446.2 → NP_197919.1  phospholipase D alpha 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_197919.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P58766
    UniProtKB/TrEMBL
    A0A654G4K6
    Conserved Domains (4) summary
    PLN02270
    Location:3 → 820
    PLN02270; phospholipase D alpha
    cd04015
    Location:5 → 156
    C2_plant_PLD; C2 domain present in plant phospholipase D (PLD)
    pfam12357
    Location:739 → 810
    PLD_C; Phospholipase D C terminal
    cl15239
    Location:500 → 708
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins
  3. NM_001343922.1 → NP_001331648.1  phospholipase D alpha 3 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BEI1, A0A654G4K6
  4. NM_001343920.1 → NP_001318645.1  phospholipase D alpha 3 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P58766
    UniProtKB/TrEMBL
    A0A654G4K6
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