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PGL5 6-phosphogluconolactonase 5 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 832513, updated on 18-Sep-2024

Summary

Official Symbol
PGL5
Official Full Name
6-phosphogluconolactonase 5
Primary source
TAIR:AT5G24420
Locus tag
AT5G24420
See related
Araport:AT5G24420
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
6-phosphogluconolactonase 5; K16H17.13; K16H17_13
Summary
Encodes a cytosolic 6-phosphogluconolactonase (PGL) thought to be involved in the oxidative pentose-phosphate pathway (OPPP).
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Genomic context

See PGL5 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
3
Sequence:
Chromosome: 5; NC_003076.8 (8336534..8338032, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene NagB/RpiA/CoA transferase-like superfamily protein Neighboring gene 6-phosphogluconolactonase 4 Neighboring gene Calcium-dependent protein kinase (CDPK) family protein Neighboring gene CTC-interacting domain 13

Pathways from PubChem

General gene information

NM_122350.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables 6-phosphogluconolactonase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in pentose-phosphate shunt IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
6-phosphogluconolactonase 5
NP_197830.1
  • 6-phosphogluconolactonase 5 (PGL5); FUNCTIONS IN: 6-phosphogluconolactonase activity; INVOLVED IN: pentose-phosphate shunt, pentose-phosphate shunt, oxidative branch, carbohydrate metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: 6-phosphogluconolactonase, DevB-type (InterPro:IPR005900); BEST Arabidopsis thaliana protein match is: 6-phosphogluconolactonase 2 (TAIR:AT3G49360.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    8336534..8338032 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_122350.4NP_197830.1  6-phosphogluconolactonase 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_197830.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8LEV7, Q9FIN0
    UniProtKB/TrEMBL
    A0A5S9Y6W9, A0A654G3Q4
    Conserved Domains (1) summary
    cl00339
    Location:8252
    SugarP_isomerase; SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to ...