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NCLPP7 nuclear-encoded CLP protease P7 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 832378, updated on 18-Sep-2024

Summary

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Official Symbol
NCLPP7
Official Full Name
nuclear-encoded CLP protease P7
Primary source
TAIR:AT5G23140
Locus tag
AT5G23140
See related
Araport:AT5G23140
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
CLPP2; MYJ24.13; MYJ24_13; nuclear-encoded CLP protease P7
Summary
One of several nuclear-encoded ClpPs (caseinolytic protease). Contains a highly conserved catalytic triad of Ser-type proteases (Ser-His-Asp). The name reflects nomenclature described in Adam et. al (2001).
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Genomic context

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See NCLPP7 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
2
Sequence:
Chromosome: 5; NC_003076.8 (7783673..7785547)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene photosystem II stability/assembly factor, chloroplast (HCF136) Neighboring gene Peptidoglycan-binding LysM domain-containing protein Neighboring gene Tudor/PWWP/MBT domain-containing protein Neighboring gene ncRNA Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mitochondrial CLPP2 Assists Coordination and Homeostasis of Respiratory Complexes. Petereit J, et al. Plant Physiol, 2020 Sep. PMID 32571844, Free PMC Article
  2. Plant mitochondria contain proteolytic and regulatory subunits of the ATP-dependent Clp protease. Halperin T, et al. Plant Mol Biol, 2001 Mar. PMID 11352464
  3. Identification of a 350-kDa ClpP protease complex with 10 different Clp isoforms in chloroplasts of Arabidopsis thaliana. Peltier JB, et al. J Biol Chem, 2001 May 11. PMID 11278690
  4. Clp protease complexes from photosynthetic and non-photosynthetic plastids and mitochondria of plants, their predicted three-dimensional structures, and functional implications. Peltier JB, et al. J Biol Chem, 2004 Feb 6. PMID 14593120
  5. Analysis of the Arabidopsis mitochondrial proteome. Millar AH, et al. Plant Physiol, 2001 Dec. PMID 11743115, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

NM_122220.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ATP-dependent peptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables cobalt ion binding HDA PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding HDA PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast stroma IDA
Inferred from Direct Assay
more info
 PubMed 
located_in chloroplast thylakoid membrane IDA
Inferred from Direct Assay
more info
 PubMed 
part_of chloroplastic endopeptidase Clp complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol HDA PubMed 
located_in mitochondrial matrix IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plastid HDA PubMed 
located_in plastid stroma IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
nuclear-encoded CLP protease P7
NP_568427.1
  • nuclear-encoded CLP protease P7 (NCLPP7); FUNCTIONS IN: cobalt ion binding, zinc ion binding; INVOLVED IN: proteolysis; LOCATED IN: in 6 components; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase S14, ClpP, active site (InterPro:IPR018215), Peptidase S14, ClpP (InterPro:IPR001907); BEST Arabidopsis thaliana protein match is: nuclear encoded CLP protease 5 (TAIR:AT1G02560.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    7783673..7785547
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_122220.5 → NP_568427.1  nuclear-encoded CLP protease P7 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_568427.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9FN42
    UniProtKB/TrEMBL
    A0A178U8I8, A0A5S9Y6F8, A0A7G2F9Q6
    Conserved Domains (1) summary
    PRK00277
    Location:31 → 225
    clpP; ATP-dependent Clp protease proteolytic subunit; Reviewed
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9FN42.1

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