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AL5 alfin-like 5 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 832173, updated on 18-Sep-2024

Summary

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Official Symbol
AL5
Official Full Name
alfin-like 5
Primary source
TAIR:AT5G20510
Locus tag
AT5G20510
See related
Araport:AT5G20510
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
alfin-like 5; F7C8.100; F7C8_100
Summary
Encodes a member of the Alfin1-like family of nuclear-localized PHD (plant homeodomain) domain containing proteins. All AL proteins except AL3 bind to di- or trimethylated histone H3 (H3K4me3/2). Members of this family include: AT5G05610 (AL1), AT3G11200 (AL2), AT3G42790 (AL3), AT5G26210 (AL4), AT5G20510 (AL5), AT2G02470 (AL6), AT1G14510 (AL7).
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Genomic context

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See AL5 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
5
Sequence:
Chromosome: 5; NC_003076.8 (6939813..6943011, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene myosin family protein with Dil Neighboring gene ncRNA Neighboring gene Glutaredoxin family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene BREVIS RADIX-like 4 Neighboring gene 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Alfin-like homeodomain finger protein AL5 suppresses multiple negative factors to confer abiotic stress tolerance in Arabidopsis. Wei W, et al. Plant J, 2015 Mar. PMID 25619813
  2. Arabidopsis AL PHD-PRC1 complexes promote seed germination through H3K4me3-to-H3K27me3 chromatin state switch in repression of seed developmental genes. Molitor AM, et al. PLoS Genet, 2014 Jan. PMID 24465219, Free PMC Article
  3. Arabidopsis ING and Alfin1-like protein families localize to the nucleus and bind to H3K4me3/2 via plant homeodomain fingers. Lee WY, et al. Plant J, 2009 May. PMID 19154204
  4. Post-transcriptional control of GRF transcription factors by microRNA miR396 and GIF co-activator affects leaf size and longevity. Debernardi JM, et al. Plant J, 2014 Aug. PMID 24888433
  5. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. AL5 inhibits multiple signaling pathways to confer stress tolerance.
    Title: The Alfin-like homeodomain finger protein AL5 suppresses multiple negative factors to confer abiotic stress tolerance in Arabidopsis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001343672.1
NM_001343673.1
NM_122058.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables histone binding IEA
Inferred from Electronic Annotation
more info
  
enables methylated histone binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables transcription corepressor activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within response to salt stress IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to water deprivation IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
alfin-like 5
NP_197551.2
  • alfin-like 5 (AL5); CONTAINS InterPro DOMAIN/s: Zinc finger, PHD-type, conserved site (InterPro:IPR019786), Protein of unknown function DUF3594 (InterPro:IPR021998), Zinc finger, PHD-type (InterPro:IPR001965), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: alfin-like 3 (TAIR:AT3G42790.1); Has 1720 Blast hits to 1673 proteins in 197 species: Archae - 0; Bacteria - 0; Metazoa - 749; Fungi - 331; Plants - 537; Viruses - 0; Other Eukaryotes - 103 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    6939813..6943011 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_122058.4 → NP_197551.2  alfin-like 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_197551.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q5XEM9
    UniProtKB/TrEMBL
    A0A178UN04, A0A5S9Y6S7, A0A7G2FFE1
    Conserved Domains (2) summary
    cd15613
    Location:206 → 256
    PHD_AL_plant; PHD finger found in plant Alfin1-like (AL) proteins
    pfam12165
    Location:13 → 140
    Alfin

  2. NM_001343672.1 → NP_001331722.1  alfin-like 5 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BEU7, A0A7G2FFE1

  3. NM_001343673.1 → NP_001331723.1  alfin-like 5 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BEQ5
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5XEM9.1

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