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Peptidase M28 family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 832094, updated on 18-Sep-2024

Summary

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Official Full Name
Peptidase M28 family protein
Primary source
TAIR:AT5G19740
Locus tag
AT5G19740
See related
Araport:AT5G19740
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
T29J13.160; T29J13_160
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Genomic context

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Location:
chromosome: 5
Exon count:
10
Sequence:
Chromosome: 5; NC_003076.8 (6673874..6676931)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Pectin lyase-like superfamily protein Neighboring gene Peroxisomal membrane 22 kDa (Mpv17/PMP22) family protein Neighboring gene Mitochondrial substrate carrier family protein Neighboring gene tubulin alpha-3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ALTERED MERISTEM PROGRAM1 suppresses ectopic stem cell niche formation in the shoot apical meristem in a largely cytokinin-independent manner. Huang W, et al. Plant Physiol, 2015 Apr. PMID 25673776, Free PMC Article
  2. MicroRNAs inhibit the translation of target mRNAs on the endoplasmic reticulum in Arabidopsis. Li S, et al. Cell, 2013 Apr 25. PMID 23622241, Free PMC Article
  3. AMP1 and CYP78A5/7 act through a common pathway to govern cell fate maintenance in Arabidopsis thaliana. Poretska O, et al. PLoS Genet, 2020 Sep. PMID 32960882, Free PMC Article
  4. Isolation of intact vacuoles and proteomic analysis of tonoplast from suspension-cultured cells of Arabidopsis thaliana. Shimaoka T, et al. Plant Cell Physiol, 2004 Jun. PMID 15215502
  5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. De novo formation of supernumerary stem cell pools was enhanced in plants mutated in both AMP1 and its paralog LIKE AMP1, indicating that they exhibit partially overlapping roles to suppress stem cell niches respecification in the peripheral zone.
    Title: ALTERED MERISTEM PROGRAM1 suppresses ectopic stem cell niche formation in the shoot apical meristem in a largely cytokinin-independent manner.
  2. Study reports that ALTERED MERISTEM PROGRAM1 (AMP1), a gene that impacts multiple developmental processes in Arabidopsis via an unknown mechanism and its paralog LIKE AMP1 (LAMP1, At5g19740) mediate the translation inhibition, but not the RNA cleavage activity, of plant miRNAs.
    Title: MicroRNAs inhibit the translation of target mRNAs on the endoplasmic reticulum in Arabidopsis.
Submit: New GeneRIF Correction

General gene information

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NM_121979.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables metallocarboxypeptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within meristem maintenance IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within regulation of meristem growth IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane ISM
Inferred from Sequence Model
more info
  
located_in vacuole HDA PubMed 

General protein information

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Preferred Names
Peptidase M28 family protein
NP_197475.2
  • Peptidase M28 family protein; FUNCTIONS IN: dipeptidase activity; INVOLVED IN: proteolysis; LOCATED IN: vacuole; CONTAINS InterPro DOMAIN/s: Protease-associated PA (InterPro:IPR003137), Transferrin receptor-like, dimerisation (InterPro:IPR007365), Peptidase M28 (InterPro:IPR007484); BEST Arabidopsis thaliana protein match is: Peptidase M28 family protein (TAIR:AT3G54720.1); Has 3567 Blast hits to 3525 proteins in 555 species: Archae - 24; Bacteria - 1302; Metazoa - 657; Fungi - 527; Plants - 315; Viruses - 0; Other Eukaryotes - 742 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    6673874..6676931
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_121979.4 → NP_197475.2  Peptidase M28 family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_197475.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7Y228
    UniProtKB/TrEMBL
    A0A5S9Y5N9, A0A654G314
    Conserved Domains (3) summary
    cd02121
    Location:94 → 300
    PA_GCPII_like; Protease-associated domain containing protein, glutamate carboxypeptidase II (GCPII)-like. This group contains various PA domain-containing proteins similar to GCPII including, GCPIII (NAALADase2) and NAALADase L. These proteins belong to the peptidase ...
    cd08022
    Location:309 → 535
    M28_PSMA_like; M28 Zn-peptidase prostate-specific membrane antigen
    pfam04253
    Location:560 → 677
    TFR_dimer; Transferrin receptor-like dimerization domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7Y228.1

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