FASS tonneau 2 (TON2) [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: FASS
Official Full Name: tonneau 2 (TON2)
Primary source: TAIR:AT5G18580
Locus tag: AT5G18580
See related: Araport:AT5G18580
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: EMB40; EMBRYO DEFECTIVE 40; FASS 1; FASS 2; FS1; GDO; GORDO; T28N17.60; T28N17_60; TON2; TONNEAU 2
Summary: fass mutants have aberrant cell shapes due to defects in arrangement of cortical microtubules. Encodes a protein highly conserved in higher plants and similar in its C-terminal part to B' regulatory subunits of type 2A protein phosphatases. Interacts with an Arabidopsis type A subunit of PP2A in the yeast two-hybrid system.
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Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

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AtOFPs regulate cell elongation by modulating microtubule orientation via direct interaction with TONNEAU2.
Title: AtOFPs regulate cell elongation by modulating microtubule orientation via direct interaction with TONNEAU2.
Microtubule branching nucleation is specifically promoted by the B'' regulatory subunit of FASS.
Title: TONNEAU2/FASS regulates the geometry of microtubule nucleation and cortical array organization in interphase Arabidopsis cells.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_121863.4

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein phosphatase regulator activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in cortical cytoskeleton organization	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within microtubule cytoskeleton organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in microtubule cytoskeleton organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in preprophase band assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of dephosphorylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within unidimensional cell growth	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	HDA more info	PubMed
located_in nucleus	HDA more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info
located_in phragmoplast	HDA more info	PubMed
located_in spindle	HDA more info	PubMed

NP_568364.1

FASS 1 (FASS); CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), EF-HAND 2 (InterPro:IPR018249), EF-hand-like domain (InterPro:IPR011992); BEST Arabidopsis thaliana protein match is: Calcium-binding EF-hand family protein (TAIR:AT5G28850.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

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