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disease resistance protein (TIR-NBS-LRR class) family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 831955, updated on 18-Sep-2024

Summary

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Official Full Name
disease resistance protein (TIR-NBS-LRR class) family protein
Primary source
TAIR:AT5G18370
Locus tag
AT5G18370
See related
Araport:AT5G18370
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F20L16.90; F20L16_90
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Genomic context

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Location:
chromosome: 5
Exon count:
7
Sequence:
Chromosome: 5; NC_003076.8 (6083401..6089041, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Disease resistance protein (TIR-NBS-LRR class) family Neighboring gene Disease resistance protein (TIR-NBS-LRR class) family Neighboring gene Ribosomal protein S5 domain 2-like superfamily protein Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles. Lolle S, et al. Cell Host Microbe, 2017 Apr 12. PMID 28407487
  2. Pronounced intraspecific haplotype divergence at the RPP5 complex disease resistance locus of Arabidopsis. Noël L, et al. Plant Cell, 1999 Nov. PMID 10559437, Free PMC Article
  3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ADP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables NAD+ nucleotidase, cyclic ADP-ribose generating IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within defense response TAS
Traceable Author Statement
more info
 PubMed 
involved_in defense response to bacterium IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
disease resistance protein (TIR-NBS-LRR class) family protein
NP_001318593.1
  • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: defense response; LOCATED IN: intrinsic to membrane; EXPRESSED IN: stem, inflorescence meristem, hypocotyl, flower, stamen; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT5G18350.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    6083401..6089041 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001343545.1 → NP_001318593.1  disease resistance protein (TIR-NBS-LRR class) family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F4JWM0
    UniProtKB/TrEMBL
    A0A654G279
    Conserved Domains (2) summary
    sd00033
    Location:665 → 687
    LRR_RI; leucine-rich repeat [structural motif]
    cl27891
    Location:57 → 1202
    LRR_3; Leucine Rich Repeat
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
F4JWM0.1

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