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SCAR4 SCAR family protein 4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 831687, updated on 18-Sep-2024

Summary

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Official Symbol
SCAR4
Official Full Name
SCAR family protein 4
Primary source
TAIR:AT5G01730
Locus tag
AT5G01730
See related
Araport:AT5G01730
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATSCAR4; F7A7.250; F7A7_250; SCAR family protein 4; WAVE3
Summary
Encodes a member of the SCAR family.These proteins are part of a complex (WAVE) complex.The SCAR subunit activates the ARP2/3 complex which in turn act as a nucleator for actin filaments.
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Genomic context

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See SCAR4 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
9
Sequence:
Chromosome: 5; NC_003076.8 (272832..277886, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene RNI-like superfamily protein Neighboring gene ncRNA Neighboring gene miscRNA Neighboring gene ncRNA Neighboring gene Nuclear transport factor 2 (NTF2) family protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis SCARs function interchangeably to meet actin-related protein 2/3 activation thresholds during morphogenesis. Zhang C, et al. Plant Cell, 2008 Apr. PMID 18424615, Free PMC Article
  2. The role of Arabidopsis SCAR genes in ARP2-ARP3-dependent cell morphogenesis. Uhrig JF, et al. Development, 2007 Mar. PMID 17267444
  3. Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles. Vidi PA, et al. J Biol Chem, 2006 Apr 21. PMID 16414959
  4. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
  5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001342607.1
NM_001342608.1
NM_001342609.1
NM_001342610.1
NM_001342611.1
NM_001342612.1
NM_001342613.1
NM_001342614.1
NM_001342615.1
NM_001342616.1
NM_120251.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of actin nucleation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of SCAR complex TAS
Traceable Author Statement
more info
 PubMed 
located_in chloroplast HDA PubMed 
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in plastoglobule HDA PubMed 

General protein information

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Preferred Names
SCAR family protein 4
NP_001318456.1
  • SCAR family protein 4 (SCAR4); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: positive regulation of actin nucleation; LOCATED IN: SCAR complex, chloroplast, plastoglobule; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 12 growth stages; BEST Arabidopsis thaliana protein match is: SCAR homolog 2 (TAIR:AT2G38440.1); Has 1330 Blast hits to 874 proteins in 188 species: Archae - 2; Bacteria - 349; Metazoa - 454; Fungi - 169; Plants - 213; Viruses - 0; Other Eukaryotes - 143 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    272832..277886 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001342607.1 → NP_001318456.1  SCAR family protein 4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q5XPJ6, Q9LCZ7
    UniProtKB/TrEMBL
    A0A5S9Y0Y0, A0A654FXX5

  2. NM_001342610.1 → NP_001330637.1  SCAR family protein 4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BBH5

  3. NM_120251.4 → NP_195793.3  SCAR family protein 4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_195793.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q5XPJ6, Q9LCZ7
    UniProtKB/TrEMBL
    A0A5S9Y0Y0, A0A654FXX5

  4. NM_001342611.1 → NP_001330636.1  SCAR family protein 4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BBH5

  5. NM_001342612.1 → NP_001330633.1  SCAR family protein 4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BBH5

  6. NM_001342613.1 → NP_001330635.1  SCAR family protein 4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BBE5

  7. NM_001342614.1 → NP_001330634.1  SCAR family protein 4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BBE9

  8. NM_001342615.1 → NP_001330639.1  SCAR family protein 4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BBE9

  9. NM_001342616.1 → NP_001330638.1  SCAR family protein 4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BBE6

  10. NM_001342609.1 → NP_001330631.1  SCAR family protein 4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UA95, A0A1P8BBE7, A0A384KVX1

  11. NM_001342608.1 → NP_001330632.1  SCAR family protein 4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BBE8
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5XPJ6.1

Gene LinkOut

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