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THO7 Tho complex subunit 7/Mft1p [ Arabidopsis thaliana (thale cress) ]

Gene ID: 831542, updated on 18-Sep-2024

Summary

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Official Symbol
THO7
Official Full Name
Tho complex subunit 7/Mft1p
Primary source
TAIR:AT5G16790
Locus tag
AT5G16790
See related
Araport:AT5G16790
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtTHO7; F5E19.130; F5E19_130
Summary
Encodes a component of the putative Arabidopsis THO/TREX complex: THO1 or HPR1 (At5g09860), THO2 (At1g24706), THO3 or TEX1 (At5g56130), THO5 (At5g42920, At1g45233), THO6 (At2g19430), and THO7 (At5g16790, At3g02950). THO/TREX complexes in animals have been implicated in the transport of mRNA precursors. Mutants of THO3/TEX1, THO1, THO6 accumulate reduced amount of small interfering (si)RNA, suggesting a role of the putative Arabidopsis THO/TREX in siRNA biosynthesis.
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Genomic context

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See THO7 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
3
Sequence:
Chromosome: 5; NC_003076.8 (5522417..5524011, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Inositol 1,3,4-trisphosphate 5/6-kinase family protein Neighboring gene myb domain protein 9 Neighboring gene SART-1 family Neighboring gene Acyl-CoA N-acyltransferases (NAT) superfamily protein Neighboring gene Protein kinase superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Putative Arabidopsis THO/TREX mRNA export complex is involved in transgene and endogenous siRNA biosynthesis. Yelina NE, et al. Proc Natl Acad Sci U S A, 2010 Aug 3. PMID 20634427, Free PMC Article
  2. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
  3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001343466.1
NM_121685.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Component Evidence Code Pubs
part_of THO complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of THO complex part of transcription export complex IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
Tho complex subunit 7/Mft1p
NP_568339.1
  • THO7; CONTAINS InterPro DOMAIN/s: Tho complex subunit 7 (InterPro:IPR018018), Tho complex subunit 7/Mft1p (InterPro:IPR008501); BEST Arabidopsis thaliana protein match is: Tho complex subunit 7/Mft1p (TAIR:AT3G02950.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    5522417..5524011 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_121685.5 → NP_568339.1  Tho complex subunit 7/Mft1p [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_568339.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0MFG2, Q8LDS5, Q9LFD9
    UniProtKB/TrEMBL
    A0A178UEM6, A0A7G2FD40
    Conserved Domains (1) summary
    pfam05615
    Location:28 → 165
    THOC7; Tho complex subunit 7

  2. NM_001343466.1 → NP_001331398.1  Tho complex subunit 7/Mft1p [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0MFG2, Q8LDS5, Q9LFD9
    UniProtKB/TrEMBL
    A0A178UEM6, A0A7G2FD40
    Conserved Domains (1) summary
    pfam05615
    Location:28 → 165
    THOC7; Tho complex subunit 7
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8LDS5.1

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