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SYN4 sister chromatid cohesion 1 protein 4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 831487, updated on 18-Sep-2024

Summary

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Official Symbol
SYN4
Official Full Name
sister chromatid cohesion 1 protein 4
Primary source
TAIR:AT5G16270
Locus tag
AT5G16270
See related
Araport:AT5G16270
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS HOMOLOG OF RAD21 3; ATRAD21.3; sister chromatid cohesion 1 protein 4; T21H19.190; T21H19_190
Summary
Encodes a SCC1/REC8 ortholog that may be involved in mitosis and may represent a mitotic cohesin.
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Genomic context

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See SYN4 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
16
Sequence:
Chromosome: 5; NC_003076.8 (5316197..5322700)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene RNA binding (RRM/RBD/RNP motifs) family protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene F-box family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The AtRAD21.1 and AtRAD21.3 Arabidopsis cohesins play a synergistic role in somatic DNA double strand break damage repair. da Costa-Nunes JA, et al. BMC Plant Biol, 2014 Dec 16. PMID 25511710, Free PMC Article
  2. Cohesin gene defects may impair sister chromatid alignment and genome stability in Arabidopsis thaliana. Schubert V, et al. Chromosoma, 2009 Oct. PMID 19533160
  3. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
  4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_121632.4

Gene Ontology Provided by TAIR

Process Evidence Code Pubs
involved_in centromeric sister chromatid cohesion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within double-strand break repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within sister chromatid cohesion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of cohesin complex IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
sister chromatid cohesion 1 protein 4
NP_197131.2
  • sister chromatid cohesion 1 protein 4 (SYN4); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: sister chromatid cohesion; LOCATED IN: nuclear chromosome; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Rad21/Rec8 like protein, C-terminal (InterPro:IPR006909), Rad21/Rec8 like protein, N-terminal (InterPro:IPR006910); BEST Arabidopsis thaliana protein match is: Rad21/Rec8-like family protein (TAIR:AT3G59550.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    5316197..5322700
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_121632.4 → NP_197131.2  sister chromatid cohesion 1 protein 4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_197131.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8W1Y0, Q940G1, Q9LF01
    UniProtKB/TrEMBL
    A0A5S9Y4L1
    Conserved Domains (2) summary
    pfam04824
    Location:972 → 1026
    Rad21_Rec8; Conserved region of Rad21 / Rec8 like protein
    pfam04825
    Location:1 → 104
    Rad21_Rec8_N; N terminus of Rad21 / Rec8 like protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8W1Y0.1

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