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GRF5 general regulatory factor 5 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 831462, updated on 18-Sep-2024

Summary

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Official Symbol
GRF5
Official Full Name
general regulatory factor 5
Primary source
TAIR:AT5G16050
Locus tag
AT5G16050
See related
Araport:AT5G16050
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F1N13.190; F1N13_190; general regulatory factor 5; GF14 UPSILON; GF14 UPSILON CHAIN
Summary
Encodes GF14 upsilon chain, a 14-3-3 gene family member.
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Genomic context

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See GRF5 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
6
Sequence:
Chromosome: 5; NC_003076.8 (5243555..5245838, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene mental retardation GTPase activating protein Neighboring gene ncRNA Neighboring gene Regulator of chromosome condensation (RCC1) family protein Neighboring gene Cytochrome c oxidase biogenesis protein Cmc1-like protein Neighboring gene TCP-1/cpn60 chaperonin family protein Neighboring gene carboxyesterase 17

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. GROWTH REGULATING FACTOR5 stimulates Arabidopsis chloroplast division, photosynthesis, and leaf longevity. Vercruyssen L, et al. Plant Physiol, 2015 Mar. PMID 25604530, Free PMC Article
  2. The Arabidopsis 14-3-3 multigene family. Wu K, et al. Plant Physiol, 1997 Aug. PMID 9276953, Free PMC Article
  3. Interaction of a 14-3-3 protein with the plant microtubule-associated protein EDE1. Pignocchi C, et al. Ann Bot, 2011 May. PMID 21558460, Free PMC Article
  4. Light modulated activity of root alkaline/neutral invertase involves the interaction with 14-3-3 proteins. Gao J, et al. Plant J, 2014 Dec. PMID 25256212
  5. Plasma Membrane CRPK1-Mediated Phosphorylation of 14-3-3 Proteins Induces Their Nuclear Import to Fine-Tune CBF Signaling during Cold Response. Liu Z, et al. Mol Cell, 2017 Apr 6. PMID 28344081

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. GRF5 stimulates chloroplast division, resulting in a higher chloroplast number per cell with a concomitant increase in chlorophyll levels.
    Title: GROWTH REGULATING FACTOR5 stimulates Arabidopsis chloroplast division, photosynthesis, and leaf longevity.
  2. 14-3-3 upsilon most strongly associates with EDE1 in its free form, but also weakly when EDE1 is bound to microtubules. [14-3-3 upsilon]
    Title: Interaction of a 14-3-3 protein with the plant microtubule-associated protein EDE1.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001343435.1
NM_121610.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ATP binding HDA PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein phosphorylated amino acid binding TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus HDA PubMed 
located_in chloroplast stroma IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
  
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in cytosol HDA PubMed 
located_in mitochondrion HDA PubMed 
located_in nuclear envelope IDA
Inferred from Direct Assay
more info
  
located_in plant-type cell wall HDA PubMed 
located_in plasma membrane HDA PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
  
located_in plastid HDA PubMed 

General protein information

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Preferred Names
general regulatory factor 5
NP_568325.1
  • general regulatory factor 5 (GRF5); FUNCTIONS IN: protein phosphorylated amino acid binding, ATP binding; INVOLVED IN: response to cadmium ion; LOCATED IN: in 6 components; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: 14-3-3 protein (InterPro:IPR000308); BEST Arabidopsis thaliana protein match is: general regulatory factor 7 (TAIR:AT3G02520.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    5243555..5245838 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_121610.4 → NP_568325.1  general regulatory factor 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_568325.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P42645
    UniProtKB/TrEMBL
    A0A178UKR5, A0A5S9Y4J2
    Conserved Domains (1) summary
    smart00101
    Location:7 → 250
    14_3_3; 14-3-3 homologues

  2. NM_001343435.1 → NP_001331015.1  general regulatory factor 5 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P42645
    UniProtKB/TrEMBL
    A0A178UKR5, A0A5S9Y4J2
    Conserved Domains (1) summary
    smart00101
    Location:7 → 250
    14_3_3; 14-3-3 homologues
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P42645.2

Gene LinkOut

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