GNA1 glucose-6-phosphate acetyltransferase 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: GNA1
Official Full Name: glucose-6-phosphate acetyltransferase 1
Primary source: TAIR:AT5G15770
Locus tag: AT5G15770
See related: Araport:AT5G15770
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AtGNA1; F14F8.150; F14F8_150; glucose-6-phosphate acetyltransferase 1
Summary: Encodes a putative glucose-6-phosphate acetyltransferase that is likely involved in UDP-N-acetylglucosamine biosynthesis. A GFP:GNA1 fusion protein localizes to the endoplasmic reticulum.
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Genomic context

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See GNA1 in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 1

Sequence:: Chromosome: 5; NC_003076.8 (5144091..5144580, complement)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

A missense mutation in GNA1 encoding gene causes growth retardation and abnormal ectopic lignin deposition under high temperature conditions.
Title: A missense mutation in the glucosamine-6-phosphate N-acetyltransferase-encoding gene causes temperature-dependent growth defects and ectopic lignin deposition in Arabidopsis.
qPCR (quantitative PCR) revealed the ubiquitous expression of AtGNA in all organs of Arabidopsis plants
Title: Crystal structure and functional characterization of a glucosamine-6-phosphate N-acetyltransferase from Arabidopsis thaliana.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_121582.2

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables glucosamine 6-phosphate N-acetyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables glucosamine 6-phosphate N-acetyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within N-acetylglucosamine metabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in UDP-N-acetylglucosamine biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	ISM Inferred from Sequence Model more info
located_in endoplasmic reticulum	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: glucose-6-phosphate acetyltransferase 1

NP_197081.1

glucose-6-phosphate acetyltransferase 1 (GNA1); FUNCTIONS IN: glucosamine 6-phosphate N-acetyltransferase activity, N-acetyltransferase activity; INVOLVED IN: metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GCN5-related N-acetyltransferase, C-terminal (InterPro:IPR022610), GCN5-related N-acetyltransferase (InterPro:IPR000182), Acyl-CoA N-acyltransferase (InterPro:IPR016181); Has 806 Blast hits to 799 proteins in 307 species: Archae - 17; Bacteria - 208; Metazoa - 186; Fungi - 170; Plants - 47; Viruses - 3; Other Eukaryotes - 175 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

5144091..5144580 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_121582.2 → NP_197081.1 glucose-6-phosphate acetyltransferase 1 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9LFU9

UniProtKB/TrEMBL

A0A178U7Q6, A0A5S9Y4G3, A0A654G1I6

Conserved Domains (1) summary

PLN02706
Location:1 → 148

PLN02706; glucosamine 6-phosphate N-acetyltransferase