U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

UBP22 ubiquitin-specific protease 22 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 830946, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
UBP22
Official Full Name
ubiquitin-specific protease 22
Primary source
TAIR:AT5G10790
Locus tag
AT5G10790
See related
Araport:AT5G10790
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
T30N20.60; T30N20_60; ubiquitin-specific protease 22; UBIQUITIN-SPECIFIC PROTEASE 22
Summary
Encodes a ubiquitin-specific protease.
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See UBP22 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
4
Sequence:
Chromosome: 5; NC_003076.8 (3410085..3413036)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Eukaryotic aspartyl protease family protein Neighboring gene ER membrane protein complex subunit-like protein Neighboring gene RNA recognition motif (RRM)-containing protein Neighboring gene enhancer of rudimentary protein Neighboring gene Major facilitator superfamily protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis. Nassrallah A, et al. Elife, 2018 Sep 7. PMID 30192741, Free PMC Article
  2. The Adaptor Protein ENY2 Is a Component of the Deubiquitination Module of the Arabidopsis SAGA Transcriptional Co-activator Complex but not of the TREX-2 Complex. Pfab A, et al. J Mol Biol, 2018 May 11. PMID 29588169
  3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis
    Title: DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis.
Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help
NM_121117.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
part_of SAGA-type complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

Go to the top of the page Help
Preferred Names
ubiquitin-specific protease 22
NP_568239.1
  • ubiquitin-specific protease 22 (UBP22); FUNCTIONS IN: ubiquitin-specific protease activity, ubiquitin thiolesterase activity, zinc ion binding; INVOLVED IN: ubiquitin-dependent protein catabolic process; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, UBP-type (InterPro:IPR001607), Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2, conserved site (InterPro:IPR018200), Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2 (InterPro:IPR001394); BEST Arabidopsis thaliana protein match is: ubiquitin-specific protease 23 (TAIR:AT5G57990.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    3410085..3413036
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001343137.1 → NP_001332186.1  ubiquitin-specific protease 22 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BG54

  2. NM_121117.2 → NP_568239.1  ubiquitin-specific protease 22 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_568239.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9FPS5, Q9LEW0
    UniProtKB/TrEMBL
    A0A178UPE9, A0A5S9Y3P0
    Conserved Domains (2) summary
    cd02660
    Location:177 → 528
    Peptidase_C19D; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam02148
    Location:56 → 116
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LEW0.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.