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ASN3 asparagine synthetase 3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 830888, updated on 18-Sep-2024

Summary

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Official Symbol
ASN3
Official Full Name
asparagine synthetase 3
Primary source
TAIR:AT5G10240
Locus tag
AT5G10240
See related
Araport:AT5G10240
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
asparagine synthetase 3; F18D22.10; F18D22_10
Summary
Encodes asparagine synthetase (ASN3).
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Genomic context

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See ASN3 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
14
Sequence:
Chromosome: 5; NC_003076.8 (3212651..3216551, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene annexin 7 Neighboring gene tRNA-Arg Neighboring gene Phototropic-responsive NPH3 family protein Neighboring gene RAB GTPase homolog H1E Neighboring gene cyclin-dependent kinase C;1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Reciprocal regulation of distinct asparagine synthetase genes by light and metabolites in Arabidopsis thaliana. Lam HM, et al. Plant J, 1998 Nov. PMID 9881155
  2. Capturing the phosphorylation and protein interaction landscape of the plant TOR kinase. Van Leene J, et al. Nat Plants, 2019 Mar. PMID 30833711
  3. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
  4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001036787.1
NM_121062.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables asparagine synthase (glutamine-hydrolyzing) activity IEA
Inferred from Electronic Annotation
more info
  
enables aspartate-ammonia ligase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-asparagine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within asparagine biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
asparagine synthetase 3
NP_001031864.1
  • asparagine synthetase 3 (ASN3); FUNCTIONS IN: asparagine synthase (glutamine-hydrolyzing) activity; INVOLVED IN: asparagine biosynthetic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Asparagine synthase (InterPro:IPR001962), Asparagine synthase, glutamine-hydrolyzing (InterPro:IPR006426), Glutamine amidotransferase, type II (InterPro:IPR017932); BEST Arabidopsis thaliana protein match is: asparagine synthetase 2 (TAIR:AT5G65010.1); Has 13137 Blast hits to 12731 proteins in 2385 species: Archae - 388; Bacteria - 8359; Metazoa - 215; Fungi - 297; Plants - 415; Viruses - 9; Other Eukaryotes - 3454 (source: NCBI BLink).
NP_196586.1
  • asparagine synthetase 3 (ASN3); FUNCTIONS IN: asparagine synthase (glutamine-hydrolyzing) activity; INVOLVED IN: asparagine biosynthetic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Asparagine synthase (InterPro:IPR001962), Asparagine synthase, glutamine-hydrolyzing (InterPro:IPR006426), Glutamine amidotransferase, type II (InterPro:IPR017932); BEST Arabidopsis thaliana protein match is: asparagine synthetase 2 (TAIR:AT5G65010.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    3212651..3216551 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_121062.5 → NP_196586.1  asparagine synthetase 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_196586.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9LEA1, Q9LFU1, Q9ZST7
    UniProtKB/TrEMBL
    A0A178UAJ4, A0A5S9Y2Y1
    Conserved Domains (3) summary
    PLN02549
    Location:1 → 577
    PLN02549; asparagine synthase (glutamine-hydrolyzing)
    cd00712
    Location:2 → 192
    AsnB; Glutamine amidotransferases class-II (GATase) asparagine synthase_B type. Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a glutaminase domain and a ...
    pfam00733
    Location:210 → 511
    Asn_synthase; Asparagine synthase

  2. NM_001036787.1 → NP_001031864.1  asparagine synthetase 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001031864.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UAJ4, A0A5S9Y2Y1, F4KGS3
    Conserved Domains (3) summary
    PLN02549
    Location:1 → 576
    PLN02549; asparagine synthase (glutamine-hydrolyzing)
    cd00712
    Location:2 → 191
    AsnB; Glutamine amidotransferases class-II (GATase) asparagine synthase_B type. Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a glutaminase domain and a ...
    pfam00733
    Location:209 → 510
    Asn_synthase; Asparagine synthase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LFU1.1

Gene LinkOut

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