TOC64-V translocon at the outer membrane of chloroplasts 64-V [Arabidopsis thaliana (thale cress)] - Gene

Summary

Go to the top of the page Help

Official Symbol: TOC64-V
Official Full Name: translocon at the outer membrane of chloroplasts 64-V
Primary source: TAIR:AT5G09420
Locus tag: AT5G09420
See related: Araport:AT5G09420
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ARABIDOPSIS THALIANA TRANSLOCON AT THE OUTER MEMBRANE OF CHLOROPLASTS 64-V; AtmtOM64; ATTOC64-V; MTOM64; OM64; outer membrane 64; T5E8.220; T5E8_220; translocon at the outer membrane of chloroplasts 64-V
Summary: Encodes one of the 36 carboxylate clamp (CC)-tetratricopeptide repeat (TPR) proteins (Prasad 2010, Pubmed ID: 20856808) with potential to interact with Hsp90/Hsp70 as co-chaperones.
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See TOC64-V in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 13

Sequence:: Chromosome: 5; NC_003076.8 (2928173..2932021)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Structural and Functional Heat Stress Responses of Chloroplasts of Arabidopsis thaliana.
Title: Structural and Functional Heat Stress Responses of Chloroplasts of Arabidopsis thaliana.
In summary, these data provide significant insight into the fine-tuning mechanisms of mitochondrial protein import mediated by phosphorylation of the cytosolic exposed receptor protein OM64.
Title: Phosphorylation of the outer membrane mitochondrial protein OM64 influences protein import into mitochondria.
the TPR domain from AtOm64 does not discriminate between the C-termini of Hsp70 and Hsp90. [AtOm64]
Title: Exploring ligand recognition, selectivity and dynamics of TPR domains of chloroplast Toc64 and mitochondria Om64 from Arabidopsis thaliana.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Homology

Orthologs from OrthoDB

NM_120979.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within protein import into mitochondrial matrix	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein import into mitochondrial matrix	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within protein targeting to mitochondrion	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	HDA more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: translocon at the outer membrane of chloroplasts 64-V

NP_196504.2

translocon at the outer membrane of chloroplasts 64-V (TOC64-V); FUNCTIONS IN: amidase activity, binding, carbon-nitrogen ligase activity, with glutamine as amido-N-donor; INVOLVED IN: protein targeting to mitochondrion; LOCATED IN: mitochondrion; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Tetratricopeptide-like helical (InterPro:IPR011990), Amidase (InterPro:IPR000120), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: translocon at the outer membrane of chloroplasts 64-III (TAIR:AT3G17970.1); Has 28606 Blast hits to 25511 proteins in 2588 species: Archae - 476; Bacteria - 13320; Metazoa - 3833; Fungi - 2411; Plants - 1768; Viruses - 0; Other Eukaryotes - 6798 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

2928173..2932021

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_120979.3 → NP_196504.2 translocon at the outer membrane of chloroplasts 64-V [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_196504.2

Status: REVIEWED

UniProtKB/Swiss-Prot

F4KCL7, Q9FY73

UniProtKB/TrEMBL

A0A178UC85, A0A5S9Y394, A0A7G2FCA3

Conserved Domains (3) summary

TIGR00990
Location:491 → 601

3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)

sd00006
Location:488 → 516

TPR; TPR repeat [structural motif]

cl18951
Location:43 → 465

Amidase