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BIM1 basic helix-loop-helix (bHLH) DNA-binding superfamily protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 830708, updated on 18-Sep-2024

Summary

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Official Symbol
BIM1
Official Full Name
basic helix-loop-helix (bHLH) DNA-binding superfamily protein
Primary source
TAIR:AT5G08130
Locus tag
AT5G08130
See related
Araport:AT5G08130
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
T22D6.70; T22D6_70
Summary
Encodes a basic helix-loop-helix (bHLH) family protein BIM1 (BES1-INTERACTING MYC-LIKE 1), involved in brassinosteroid signaling. It synergistically interacts with BES1 to bind to E box sequences (CANNTG). Positively modulates the shade avoidance syndrome in Arabidopsis seedlings.
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Genomic context

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See BIM1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
12
Sequence:
Chromosome: 5; NC_003076.8 (2606002..2610250, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene UBQ, helicase-c and DEAD-like helicase domain-containing protein Neighboring gene movement protein binding protein 2C Neighboring gene ncRNA Neighboring gene RING/U-box superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. UVR8 Interacts with BES1 and BIM1 to Regulate Transcription and Photomorphogenesis in Arabidopsis. Liang T, et al. Dev Cell, 2018 Feb 26. PMID 29398622
  2. BIM1, a bHLH protein involved in brassinosteroid signalling, controls Arabidopsis embryonic patterning via interaction with DORNROSCHEN and DORNROSCHEN-LIKE. Chandler JW, et al. Plant Mol Biol, 2009 Jan. PMID 18830673
  3. Regulation of the Arabidopsis root vascular initial population by LONESOME HIGHWAY. Ohashi-Ito K, et al. Development, 2007 Aug. PMID 17626058, Free PMC Article
  4. A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis. Yin Y, et al. Cell, 2005 Jan 28. PMID 15680330
  5. The bHLH proteins BEE and BIM positively modulate the shade avoidance syndrome in Arabidopsis seedlings. Cifuentes-Esquivel N, et al. Plant J, 2013 Sep. PMID 23763263

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001125718.1
NM_001203328.2
NM_001203329.1
NM_001203330.2
NM_001342983.1
NM_001342984.1
NM_001342986.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables transcription cis-regulatory region binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within brassinosteroid mediated signaling pathway IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within positive regulation of shade avoidance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of DNA-templated transcription TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
basic helix-loop-helix (bHLH) DNA-binding superfamily protein
NP_001119190.1
  • BIM1; FUNCTIONS IN: protein binding, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: brassinosteroid mediated signaling pathway, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: BES1-interacting Myc-like protein 2 (TAIR:AT1G69010.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_001190257.1
  • BIM1; FUNCTIONS IN: protein binding, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: brassinosteroid mediated signaling pathway, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: BES1-interacting Myc-like protein 2 (TAIR:AT1G69010.1).
NP_001190258.1
  • BIM1; FUNCTIONS IN: protein binding, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: brassinosteroid mediated signaling pathway, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: BES1-interacting Myc-like protein 2 (TAIR:AT1G69010.1).
NP_001190259.1
  • BIM1; FUNCTIONS IN: protein binding, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: brassinosteroid mediated signaling pathway, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: BES1-interacting Myc-like protein 2 (TAIR:AT1G69010.1).
NP_001318507.1
  • BIM1; FUNCTIONS IN: protein binding, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: brassinosteroid mediated signaling pathway, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: BES1-interacting Myc-like protein 2 (TAIR:AT1G69010.1); Has 2460 Blast hits to 2449 proteins in 184 species: Archae - 0; Bacteria - 2; Metazoa - 308; Fungi - 82; Plants - 2059; Viruses - 0; Other Eukaryotes - 9 (source: NCBI BLink).
NP_001318508.1
  • basic helix-loop-helix (bHLH) DNA-binding superfamily protein; FUNCTIONS IN: protein binding, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: brassinosteroid mediated signaling pathway, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: BES1-interacting Myc-like protein 2 (TAIR:AT1G69010.1); Has 2462 Blast hits to 2451 proteins in 182 species: Archae - 0; Bacteria - 2; Metazoa - 310; Fungi - 80; Plants - 2061; Viruses - 0; Other Eukaryotes - 9 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    2606002..2610250 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001342985.1 → NP_001330723.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UF90, A0A1P8BBN4

  2. NM_001203330.2 → NP_001190259.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001190259.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UF90, F4K9L3
    Conserved Domains (1) summary
    pfam00010
    Location:282 → 331
    HLH; Helix-loop-helix DNA-binding domain

  3. NM_001342984.1 → NP_001318508.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A7G2F7Y2, F4K9L4

  4. NM_001203328.2 → NP_001190257.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001190257.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A1L4Z3, Q9LEZ3
    UniProtKB/TrEMBL
    A0A178UDI1
    Conserved Domains (1) summary
    pfam00010
    Location:278 → 327
    HLH; Helix-loop-helix DNA-binding domain

  5. NM_001342986.1 → NP_001330724.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UDI1, A0A1P8BBP3

  6. NM_001342983.1 → NP_001318507.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A7G2F607, C0SVN9

  7. NM_001125718.1 → NP_001119190.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001119190.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A1L4Z3, Q9LEZ3
    UniProtKB/TrEMBL
    A0A178UDI1
    Conserved Domains (1) summary
    pfam00010
    Location:278 → 327
    HLH; Helix-loop-helix DNA-binding domain

  8. NM_001203329.1 → NP_001190258.1  basic helix-loop-helix (bHLH) DNA-binding superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001190258.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UDI1, F4K9L2
    Conserved Domains (1) summary
    pfam00010
    Location:278 → 327
    HLH; Helix-loop-helix DNA-binding domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LEZ3.2

Gene LinkOut

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