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FH19 Actin-binding FH2 (formin homology 2) family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 830671, updated on 18-Sep-2024

Summary

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Official Symbol
FH19
Official Full Name
Actin-binding FH2 (formin homology 2) family protein
Primary source
TAIR:AT5G07780
Locus tag
AT5G07780
See related
Araport:AT5G07780
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtFH19; formin homolog 19; MXM12.2; MXM12_2
Summary
Encodes a class II formin that nucleates actin assembly, binds to the barbed-end of actin filaments and antagonizes the effect of FH1 on actin dynamics.
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Genomic context

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See FH19 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
14
Sequence:
Chromosome: 5; NC_003076.8 (2479514..2482850)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene formin homology 2 domain-containing protein / FH2 domain-containing protein Neighboring gene Actin-binding FH2 protein Neighboring gene uncharacterized protein Neighboring gene Flavin-binding monooxygenase family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An Arabidopsis class II formin, AtFH19, nucleates actin assembly, binds to the barbed end of actin filaments, and antagonizes the effect of AtFH1 on actin dynamics. Zheng Y, et al. J Integr Plant Biol, 2012 Oct. PMID 22947203
  2. Formin homology 2 domains occur in multiple contexts in angiosperms. Cvrcková F, et al. BMC Genomics, 2004 Jul 15. PMID 15256004, Free PMC Article
  3. Formins: intermediates in signal-transduction cascades that affect cytoskeletal reorganization. Deeks MJ, et al. Trends Plant Sci, 2002 Nov. PMID 12417149
  4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. An Arabidopsis class II formin, AtFH19, nucleates actin assembly, binds to the barbed end of actin filaments, and antagonizes the effect of AtFH1 on actin dynamics. [AtFH19]
    Title: An Arabidopsis class II formin, AtFH19, nucleates actin assembly, binds to the barbed end of actin filaments, and antagonizes the effect of AtFH1 on actin dynamics.
Submit: New GeneRIF Correction

General gene information

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Homology

NM_120860.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables actin binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within actin nucleation IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within barbed-end actin filament capping IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
Actin-binding FH2 (formin homology 2) family protein
NP_196395.1
  • Actin-binding FH2 (formin homology 2) family protein; FUNCTIONS IN: actin binding; INVOLVED IN: cellular component organization, actin cytoskeleton organization; LOCATED IN: chloroplast; EXPRESSED IN: root, flower; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Actin-binding FH2/DRF autoregulatory (InterPro:IPR003104), Actin-binding FH2 (InterPro:IPR015425); BEST Arabidopsis thaliana protein match is: actin binding (TAIR:AT5G07740.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    2479514..2482850
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_120860.3 → NP_196395.1  Actin-binding FH2 (formin homology 2) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_196395.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9FF14
    UniProtKB/TrEMBL
    A0A5S9Y2W5, A0A654FZ93
    Conserved Domains (1) summary
    pfam02181
    Location:68 → 437
    FH2; Formin Homology 2 Domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9FF14.1

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