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SPC98 spindle pole body component 98 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 830557, updated on 18-Sep-2024

Summary

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Official Symbol
SPC98
Official Full Name
spindle pole body component 98
Primary source
TAIR:AT5G06680
Locus tag
AT5G06680
See related
Araport:AT5G06680
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA GAMMA TUBULIN COMPLEX PROTEIN 3; ATGCP3; ATSPC98; GAMMA TUBULIN COMPLEX PROTEIN 3; GCP3; MPH15.2; MPH15_2; spindle pole body component 98; SPINDLE POLE BODY COMPONENT 98
Summary
Encodes protein similar to yeast SCP98. Yeast SCP98 is essential for the microtubule nucleation activity of the gamma-tubulin ring complexes. Enriched at the post-cytokinetic cell edges in leaves and roots.
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Genomic context

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See SPC98 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
2
Sequence:
Chromosome: 5; NC_003076.8 (2056528..2059859)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene transmembrane/coiled-coil protein (Protein of unknown function DUF106, transmembrane) Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene tRNA-Ser Neighboring gene WCRKC thioredoxin 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The plant Spc98p homologue colocalizes with gamma-tubulin at microtubule nucleation sites and is required for microtubule nucleation. Erhardt M, et al. J Cell Sci, 2002 Jun 1. PMID 12006626
  2. The Arabidopsis AtGCD3 protein is a glucosylceramidase that preferentially hydrolyzes long-acyl-chain glucosylceramides. Dai GY, et al. J Biol Chem, 2020 Jan 17. PMID 31819005, Free PMC Article
  3. Cell edges accumulate gamma tubulin complex components and nucleate microtubules following cytokinesis in Arabidopsis thaliana. Ambrose C, et al. PLoS One, 2011. PMID 22110647, Free PMC Article
  4. Microtubule and katanin-dependent dynamics of microtubule nucleation complexes in the acentrosomal Arabidopsis cortical array. Nakamura M, et al. Nat Cell Biol, 2010 Nov. PMID 20935636
  5. A mutation in the Arabidopsis gamma-tubulin-containing complex causes helical growth and abnormal microtubule branching. Nakamura M, et al. J Cell Sci, 2009 Jul 1. PMID 19509058

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The Arabidopsis AtGCD3 protein is a glucosylceramidase that preferentially hydrolyzes long-acyl-chain glucosylceramides.
    Title: The Arabidopsis AtGCD3 protein is a glucosylceramidase that preferentially hydrolyzes long-acyl-chain glucosylceramides.
  2. gamma tubulin nucleation complex (GCP2 and GCP3) localize at distinct sites along the outer periclinal edge of newly formed crosswalls
    Title: Cell edges accumulate gamma tubulin complex components and nucleate microtubules following cytokinesis in Arabidopsis thaliana.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_120751.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables gamma-tubulin binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables tubulin binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within microtubule nucleation TAS
Traceable Author Statement
more info
 PubMed 
involved_in positive regulation of microtubule nucleation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in response to nematode IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cell cortex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cortical microtubule IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasmic side of plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
part_of gamma-tubulin complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in microtubule IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nuclear envelope IDA
Inferred from Direct Assay
more info
 PubMed 
located_in spindle IDA
Inferred from Direct Assay
more info
 PubMed 
located_in spindle pole IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
spindle pole body component 98
NP_196286.1
  • spindle pole body component 98 (SPC98); CONTAINS InterPro DOMAIN/s: Spc97/Spc98 (InterPro:IPR007259), Gamma tubulin complex protein 3 (InterPro:IPR015697); BEST Arabidopsis thaliana protein match is: Spc97 / Spc98 family of spindle pole body (SBP) component (TAIR:AT5G17410.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    2056528..2059859
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_120751.4 → NP_196286.1  spindle pole body component 98 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_196286.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9FG37
    UniProtKB/TrEMBL
    A0A178UFG2, A0A5S9Y1Z7, A0A654FYV7
    Conserved Domains (2) summary
    pfam04130
    Location:499 → 831
    Spc97_Spc98; Spc97 / Spc98 family
    pfam17681
    Location:190 → 493
    GCP_N_terminal; Gamma tubulin complex component N-terminal
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9FG37.1

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