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SIR sulfite reductase [ Arabidopsis thaliana (thale cress) ]

Gene ID: 830336, updated on 18-Sep-2024

Summary

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Official Symbol
SIR
Official Full Name
sulfite reductase
Primary source
TAIR:AT5G04590
Locus tag
AT5G04590
See related
Araport:AT5G04590
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
sulfite reductase; SULFITE REDUCTASE; T1E3.2
Summary
A.thaliana gene encoding sulfite reductase.
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Genomic context

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See SIR in Genome Data Viewer
Location:
chromosome: 5
Exon count:
8
Sequence:
Chromosome: 5; NC_003076.8 (1319074..1323364)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene type-1 restriction enzyme mjaxp r protein (DUF668) Neighboring gene HhH-GPD base excision DNA repair family protein Neighboring gene RNA-binding (RRM/RBD/RNP motifs) family protein Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene biotin F

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sulfite reductase defines a newly discovered bottleneck for assimilatory sulfate reduction and is essential for growth and development in Arabidopsis thaliana. Khan MS, et al. Plant Cell, 2010 Apr. PMID 20424176, Free PMC Article
  2. Isolation and characterization of a gene for assimilatory sulfite reductase from Arabidopsis thaliana. Bork C, et al. Gene, 1998 May 28. PMID 9661674
  3. Sulfite reductase protects plants against sulfite toxicity. Yarmolinsky D, et al. Plant Physiol, 2013 Feb. PMID 23221833, Free PMC Article
  4. The chloroplast lumen and stromal proteomes of Arabidopsis thaliana show differential sensitivity to short- and long-term exposure to low temperature. Goulas E, et al. Plant J, 2006 Sep. PMID 16923014
  5. Divalent metal ions in plant mitochondria and their role in interactions with proteins and oxidative stress-induced damage to respiratory function. Tan YF, et al. Plant Physiol, 2010 Feb. PMID 20018591, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data indicate a rapid up-regulation of sulfite reductase (SiR) transcript and activity within 30 min of sulfite injection into Arabidopsis and tomato leaves.
    Title: Sulfite reductase protects plants against sulfite toxicity.
  2. SiR is essential for normal growth. Downregulation causes severe adaptive reactions of primary and secondary metabolism.
    Title: Sulfite reductase defines a newly discovered bottleneck for assimilatory sulfate reduction and is essential for growth and development in Arabidopsis thaliana.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_120541.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables copper ion binding HDA PubMed 
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables sulfite reductase (ferredoxin) activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables sulfite reductase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of DNA-templated transcription ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within response to cold IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within sulfate assimilation TAS
Traceable Author Statement
more info
  
involved_in sulfide oxidation ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within sulfur compound metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in apoplast HDA PubMed 
located_in chloroplast HDA PubMed 
located_in chloroplast envelope HDA PubMed 
located_in chloroplast nucleoid ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in chloroplast stroma HDA PubMed 
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
NOT located_in cytosol RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in plasma membrane HDA PubMed 
located_in plastid TAS
Traceable Author Statement
more info
 PubMed 
located_in stromule IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
sulfite reductase
NP_196079.1
  • sulfite reductase (SIR); FUNCTIONS IN: sulfite reductase activity, sulfite reductase (ferredoxin) activity, copper ion binding; INVOLVED IN: sulfate reduction, response to salt stress, response to cold; LOCATED IN: in 7 components; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Sulphite reductase, ferredoxin dependent (InterPro:IPR011787), Nitrite/sulphite reductase iron-sulphur/siroheam-binding site (InterPro:IPR006066), Nitrite/sulphite reductase 4Fe-4S domain (InterPro:IPR006067), Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like (InterPro:IPR005117); BEST Arabidopsis thaliana protein match is: nitrite reductase 1 (TAIR:AT2G15620.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    1319074..1323364
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_120541.4 → NP_196079.1  sulfite reductase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_196079.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O23650, Q0WMF4, Q42590, Q94AB9, Q9LZ66
    UniProtKB/TrEMBL
    A0A178UPZ1, A0A5S9Y232, A0A654FY85
    Conserved Domains (1) summary
    PLN00178
    Location:24 → 642
    PLN00178; sulfite reductase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LZ66.1

Gene LinkOut

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