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KCS19 3-ketoacyl-CoA synthase 19 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 830332, updated on 18-Sep-2024

Summary

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Official Symbol
KCS19
Official Full Name
3-ketoacyl-CoA synthase 19
Primary source
TAIR:AT5G04530
Locus tag
AT5G04530
See related
Araport:AT5G04530
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
3-ketoacyl-CoA synthase 19; T32M21.130; T32M21_130
Summary
Encodes KCS19, a member of the 3-ketoacyl-CoA synthase family involved in the biosynthesis of VLCFA (very long chain fatty acids).
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Genomic context

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See KCS19 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
1
Sequence:
Chromosome: 5; NC_003076.8 (1291630..1293723, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene glycosyltransferase family protein 47 Neighboring gene 3'-phosphoinositide-dependent protein kinase 1 Neighboring gene 3-oxoacyl-acyl-carrier synthase-like protein (Protein of unknown function DUF455) Neighboring gene ncRNA Neighboring gene Myotubularin-like phosphatases II superfamily

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of the closely related Arabidopsis thaliana β-ketoacyl-CoA synthases KCS3, KCS12 and KCS19. Zhang Z, et al. Plant J, 2024 Jul. PMID 38666591
  2. The VLCFA elongase gene family in Arabidopsis thaliana: phylogenetic analysis, 3D modelling and expression profiling. Joubès J, et al. Plant Mol Biol, 2008 Jul. PMID 18465198
  3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Characterization of the closely related Arabidopsis thaliana beta-ketoacyl-CoA synthases KCS3, KCS12 and KCS19.
    Title: Characterization of the closely related Arabidopsis thaliana β-ketoacyl-CoA synthases KCS3, KCS12 and KCS19.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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NM_120535.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables fatty acid elongase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to cold IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to light stimulus IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
3-ketoacyl-CoA synthase 19
NP_196073.1
  • 3-ketoacyl-CoA synthase 19 (KCS19); FUNCTIONS IN: transferase activity, transferring acyl groups other than amino-acyl groups, catalytic activity, acyltransferase activity; INVOLVED IN: response to cold, response to light stimulus, response to osmotic stress; LOCATED IN: endomembrane system, membrane; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Thiolase-like (InterPro:IPR016039), Very-long-chain 3-ketoacyl-CoA synthase (InterPro:IPR012392), 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal (InterPro:IPR013747), FAE1/Type III polyketide synthase-like protein (InterPro:IPR013601), Thiolase-like, subgroup (InterPro:IPR016038); BEST Arabidopsis thaliana protein match is: 3-ketoacyl-CoA synthase 12 (TAIR:AT2G28630.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    1291630..1293723 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_120535.3 → NP_196073.1  3-ketoacyl-CoA synthase 19 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_196073.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9LZ72
    UniProtKB/TrEMBL
    A0A178UE05, A0A5S9Y1M4
    Conserved Domains (2) summary
    pfam08392
    Location:24 → 317
    FAE1_CUT1_RppA; FAE1/Type III polyketide synthase-like protein
    cl21486
    Location:337 → 410
    Ketoacyl-synt_C; Beta-ketoacyl synthase, C-terminal domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LZ72.1

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