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POR C-CAP/cofactor C-like domain-containing protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 830151, updated on 18-Sep-2024

Summary

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Official Symbol
POR
Official Full Name
C-CAP/cofactor C-like domain-containing protein
Primary source
TAIR:AT4G39920
Locus tag
AT4G39920
See related
Araport:AT4G39920
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
PORCINO; T5J17.90; T5J17_90; TFC C; TUBULIN-FOLDING COFACTOR C
Summary
Microtubule-folding cofactor, produces assembly-competent alpha-/beta-tubulin heterodimers.
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Genomic context

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See POR in Genome Data Viewer
Location:
chromosome: 4
Exon count:
1
Sequence:
Chromosome: 4; NC_003075.7 (18515693..18517302)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene ubiquitin-specific protease 3 Neighboring gene low-molecular-weight cysteine-rich 45 Neighboring gene AT hook motif DNA-binding family protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional analysis of the tubulin-folding cofactor C in Arabidopsis thaliana. Kirik V, et al. Curr Biol, 2002 Sep 3. PMID 12225668
  2. FC2 stabilizes POR and suppresses ALA formation in the tetrapyrrole biosynthesis pathway. Fan T, et al. New Phytol, 2023 Jul. PMID 37161708
  3. Mutations in the pilz group genes disrupt the microtubule cytoskeleton and uncouple cell cycle progression from cell division in Arabidopsis embryo and endosperm. Mayer U, et al. Eur J Cell Biol, 1999 Feb. PMID 10099932
  4. The Arabidopsis PILZ group genes encode tubulin-folding cofactor orthologs required for cell division but not cell growth. Steinborn K, et al. Genes Dev, 2002 Apr 15. PMID 11959844, Free PMC Article
  5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. FC2 stabilizes POR and suppresses ALA formation in the tetrapyrrole biosynthesis pathway.
    Title: FC2 stabilizes POR and suppresses ALA formation in the tetrapyrrole biosynthesis pathway.
Submit: New GeneRIF Correction

General gene information

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NM_120155.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables tubulin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cytokinesis by cell plate formation IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in microtubule cytoskeleton organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in post-chaperonin tubulin folding pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within tubulin complex assembly IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within tubulin complex assembly ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
C-CAP/cofactor C-like domain-containing protein
NP_195702.1
  • PORCINO (POR); FUNCTIONS IN: binding; INVOLVED IN: tubulin complex assembly, cytokinesis; LOCATED IN: cytoplasm; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: CARP motif (InterPro:IPR006599), C-CAP/cofactor C-like domain (InterPro:IPR017901), Tubulin binding cofactor C (InterPro:IPR012945); Has 497 Blast hits to 493 proteins in 165 species: Archae - 0; Bacteria - 11; Metazoa - 222; Fungi - 88; Plants - 54; Viruses - 0; Other Eukaryotes - 122 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    18515693..18517302
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_120155.4 → NP_195702.1  C-CAP/cofactor C-like domain-containing protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_195702.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8L5R4, Q9SMR2
    UniProtKB/TrEMBL
    A0A178UWP1, A0A5S9Y2E6
    Conserved Domains (2) summary
    pfam07986
    Location:199 → 316
    TBCC; Tubulin binding cofactor C
    pfam16752
    Location:17 → 139
    TBCC_N; Tubulin-specific chaperone C N-terminal domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SMR2.1

Gene LinkOut

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