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ELI3-2 cinnamyl alcohol dehydrogenase 8 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 829955, updated on 18-Sep-2024

Summary

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Official Symbol
ELI3-2
Official Full Name
cinnamyl alcohol dehydrogenase 8
Primary source
TAIR:AT4G37990
Locus tag
AT4G37990
See related
Araport:AT4G37990
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA CINNAMYL-ALCOHOL DEHYDROGENASE 8; ATCAD8; CAD-B2; CI0009; CINNAMYL-ALCOHOL DEHYDROGENASE; CINNAMYL-ALCOHOL DEHYDROGENASE B2; ELI3; ELICITOR-ACTIVATED GENE 3; elicitor-activated gene 3-2; F20D10.110; F20D10_110
Summary
Encodes an aromatic alcohol:NADP+ oxidoreductase whose mRNA levels are increased in response to treatment with a variety of phytopathogenic bacteria. Though similar to mannitol dehydrogenases, this enzyme does not have mannitol dehydrogenase activity.
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Genomic context

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See ELI3-2 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
4
Sequence:
Chromosome: 4; NC_003075.7 (17855637..17857878)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene cinnamyl alcohol dehydrogenase 6 Neighboring gene cinnamyl alcohol dehydrogenase 7 Neighboring gene DNA binding with one finger 4.7 Neighboring gene uncharacterized protein Neighboring gene Pentatricopeptide repeat (PPR-like) superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis thaliana defense-related protein ELI3 is an aromatic alcohol:NADP+ oxidoreductase. Somssich IE, et al. Proc Natl Acad Sci U S A, 1996 Nov 26. PMID 11038530, Free PMC Article
  2. Rapid activation of a novel plant defense gene is strictly dependent on the Arabidopsis RPM1 disease resistance locus. Kiedrowski S, et al. EMBO J, 1992 Dec. PMID 1464303, Free PMC Article
  3. Expression of cinnamyl alcohol dehydrogenases and their putative homologues during Arabidopsis thaliana growth and development: lessons for database annotations? Kim SJ, et al. Phytochemistry, 2007 Jul. PMID 17467016
  4. Functional reclassification of the putative cinnamyl alcohol dehydrogenase multigene family in Arabidopsis. Kim SJ, et al. Proc Natl Acad Sci U S A, 2004 Feb 10. PMID 14745009, Free PMC Article
  5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

NM_119960.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables aryl-alcohol dehydrogenase (NADP+) activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables cinnamyl-alcohol dehydrogenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables cinnamyl-alcohol dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
NOT enables mannitol dehydrogenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in lignin biosynthetic process IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within plant-type hypersensitive response IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within response to bacterium IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in plasma membrane HDA PubMed 

General protein information

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Preferred Names
cinnamyl alcohol dehydrogenase 8
NP_195512.1
  • elicitor-activated gene 3-2 (ELI3-2); CONTAINS InterPro DOMAIN/s: GroES-like (InterPro:IPR011032), Alcohol dehydrogenase GroES-like (InterPro:IPR013154), Alcohol dehydrogenase, zinc-containing, conserved site (InterPro:IPR002328), Alcohol dehydrogenase, C-terminal (InterPro:IPR013149), Alcohol dehydrogenase superfamily, zinc-containing (InterPro:IPR002085); BEST Arabidopsis thaliana protein match is: elicitor-activated gene 3-1 (TAIR:AT4G37980.1); Has 39982 Blast hits to 39962 proteins in 3075 species: Archae - 828; Bacteria - 26485; Metazoa - 1263; Fungi - 3046; Plants - 3202; Viruses - 3; Other Eukaryotes - 5155 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    17855637..17857878
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_119960.3 → NP_195512.1  cinnamyl alcohol dehydrogenase 8 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_195512.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q02972, Q53ZN2
    UniProtKB/TrEMBL
    A0A178UVK9, A0A5S9XZX2
    Conserved Domains (1) summary
    cd05283
    Location:10 → 348
    CAD1; Cinnamyl alcohol dehydrogenases (CAD)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q02972.1

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