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GBF1 G-box binding factor 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 829826, updated on 18-Sep-2024

Summary

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Official Symbol
GBF1
Official Full Name
G-box binding factor 1
Primary source
TAIR:AT4G36730
Locus tag
AT4G36730
See related
Araport:AT4G36730
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AP22.21; AP22_21; AtGBF1; G-box binding factor 1
Summary
member of a gene family encoding basic leucine zipper proteins (GBFs) which bind the G-box
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Genomic context

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See GBF1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
12
Sequence:
Chromosome: 4; NC_003075.7 (17309612..17312488, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene GRAS family transcription factor Neighboring gene ncRNA Neighboring gene HVA22-like protein K Neighboring gene ncRNA Neighboring gene homeobox protein 40 Neighboring gene Quinone reductase family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Polarized cell growth in Arabidopsis requires endosomal recycling mediated by GBF1-related ARF exchange factors. Richter S, et al. Nat Cell Biol, 2011 Dec 4. PMID 22138577
  2. HY1 genetically interacts with GBF1 and regulates the activity of the Z-box containing promoters in light signaling pathways in Arabidopsis thaliana. Prasad VB, et al. Mech Dev, 2012 Sep-Dec. PMID 22766018
  3. The AtCathB3 gene, encoding a cathepsin B-like protease, is expressed during germination of Arabidopsis thaliana and transcriptionally repressed by the basic leucine zipper protein GBF1. Iglesias-Fernández R, et al. J Exp Bot, 2014 May. PMID 24600022, Free PMC Article
  4. Redox-mediated mechanisms regulate DNA binding activity of the G-group of basic region leucine zipper (bZIP) transcription factors in Arabidopsis. Shaikhali J, et al. J Biol Chem, 2012 Aug 10. PMID 22718771, Free PMC Article
  5. Heterodimerization between light-regulated and ubiquitously expressed Arabidopsis GBF bZIP proteins. Schindler U, et al. EMBO J, 1992 Apr. PMID 1373374, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. An interplay between bZIP16, bZIP68, and GBF1 regulates nuclear photosynthetic genes during photomorphogenesis in Arabidopsis.
    Title: An interplay between bZIP16, bZIP68, and GBF1 regulates nuclear photosynthetic genes during photomorphogenesis in Arabidopsis.
  2. This study reveals that MYC2 and GBF1 colocalize and physically interact in the nucleus. This interaction requires the N-terminal domain of each protein.
    Title: Interaction of MYC2 and GBF1 results in functional antagonism in blue light-mediated Arabidopsis seedling development.
  3. GBF1 is a transcriptional repressor of the AtCathB3 gene and affects germination kinetics of A. thaliana seeds. As AtCathB3 is also expressed during post-germination in cotyledons, a role for the AtCathB3-like protease in reserve mobilization is inferred.
    Title: The AtCathB3 gene, encoding a cathepsin B-like protease, is expressed during germination of Arabidopsis thaliana and transcriptionally repressed by the basic leucine zipper protein GBF1.
  4. The DNA binding activity of GBF1 is modulated by heterodimeriation with HY5 and HYH.
    Title: Genome-wide DNA binding of GBF1 is modulated by its heterodimerizing protein partners, HY5 and HYH.
  5. Genetic interactions of HY1 and GBF1 in seedling photomorphogenesis.
    Title: HY1 genetically interacts with GBF1 and regulates the activity of the Z-box containing promoters in light signaling pathways in Arabidopsis thaliana.
  6. the functional interrelations of GBF1 with HY5 and HYH in Arabidopsis seedling development.
    Title: Molecular interactions of GBF1 with HY5 and HYH proteins during light-mediated seedling development in Arabidopsis thaliana.
  7. In Arabidopsis, GBF1-related exchange factors for the ARF GTPases (ARF GEFs) GNOM and GNL2 play essential roles in polar tip growth of root hairs and pollen, respectively.
    Title: Polarized cell growth in Arabidopsis requires endosomal recycling mediated by GBF1-related ARF exchange factors.
  8. GBF1, a transcription factor of blue light signaling in Arabidopsis, is degraded in the dark by a proteasome-mediated pathway independent of COP1 and SPA1
    Title: GBF1, a transcription factor of blue light signaling in Arabidopsis, is degraded in the dark by a proteasome-mediated pathway independent of COP1 and SPA1.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_119837.4
NM_179179.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables transcription cis-regulatory region binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
G-box binding factor 1
NP_195391.1
  • G-box binding factor 1 (GBF1); CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), G-box binding, MFMR (InterPro:IPR012900), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: basic region/leucine zipper transcription factor 16 (TAIR:AT2G35530.1); Has 3905 Blast hits to 3842 proteins in 356 species: Archae - 8; Bacteria - 123; Metazoa - 1421; Fungi - 442; Plants - 1419; Viruses - 137; Other Eukaryotes - 355 (source: NCBI BLink).
NP_849510.1
  • G-box binding factor 1 (GBF1); CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), G-box binding, MFMR (InterPro:IPR012900), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: basic region/leucine zipper transcription factor 16 (TAIR:AT2G35530.1); Has 3891 Blast hits to 3827 proteins in 347 species: Archae - 8; Bacteria - 109; Metazoa - 1441; Fungi - 440; Plants - 1415; Viruses - 137; Other Eukaryotes - 341 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    17309612..17312488 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_179179.3 → NP_849510.1  G-box binding factor 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_849510.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9XZX0, A0A7G2F6E6
    Conserved Domains (4) summary
    smart00338
    Location:218 → 282
    BRLZ; basic region leucin zipper
    cd14702
    Location:223 → 274
    bZIP_plant_GBF1; coiled coil [structural motif]
    pfam07777
    Location:1 → 94
    MFMR; G-box binding protein MFMR
    pfam16596
    Location:129 → 209
    MFMR_assoc; Disordered region downstream of MFMR

  2. NM_119837.4 → NP_195391.1  G-box binding factor 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_195391.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P42774, Q940I9, Q944J1, Q96263
    UniProtKB/TrEMBL
    A0A178V1V9, A0A384KK13, A0A5S9XZX0, Q5K1L6
    Conserved Domains (3) summary
    smart00338
    Location:220 → 284
    BRLZ; basic region leucin zipper
    cd14702
    Location:225 → 276
    bZIP_plant_GBF1; coiled coil [structural motif]
    pfam07777
    Location:1 → 94
    MFMR; G-box binding protein MFMR
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P42774.2

Gene LinkOut

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