CST Protein kinase superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: CST
Official Full Name: Protein kinase superfamily protein
Primary source: TAIR:AT4G35600
Locus tag: AT4G35600
See related: Araport:AT4G35600
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: CAST AWAY; CONNEXIN 32; CX32; F8D20.110; F8D20_110; Kin4; kinase 4
Summary: Encodes a receptor-like cytoplasmic kinase that acts as a spatial inhibitor of cell separation. Analysis of the cDNA previously described in Meiners et al., 1991 revealed mistakes in the predicted open reading frame.
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Genomic context

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See CST in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 6

Sequence:: Chromosome: 4; NC_003075.7 (16896153..16898933)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The characterization of CAST AWAY (CST), a receptor-like cytoplasmic kinase that acts as a spatial inhibitor of cell separation, is reported.[CAST AWAY] [CST]
Title: CAST AWAY, a membrane-associated receptor-like kinase, inhibits organ abscission in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_001203999.1

Supported by ESTs:

NM_119725.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein kinase activity	IDA Inferred from Direct Assay more info	PubMed
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within abscission	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of floral organ abscission	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
NOT located_in chloroplast	IDA Inferred from Direct Assay more info	PubMed
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	HDA more info	PubMed
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: Protein kinase superfamily protein

NP_001190928.1

CONNEXIN 32; FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT2G17220.2).

NP_195285.3

CONNEXIN 32; FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation, N-terminal protein myristoylation; LOCATED IN: plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT2G17220.2); Has 113047 Blast hits to 111623 proteins in 3982 species: Archae - 93; Bacteria - 12910; Metazoa - 41769; Fungi - 9485; Plants - 32138; Viruses - 364; Other Eukaryotes - 16288 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

16896153..16898933

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_119725.5 → NP_195285.3 Protein kinase superfamily protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_195285.3

Status: REVIEWED

UniProtKB/Swiss-Prot

O81792, P27450, Q8VZ07, Q9M068

UniProtKB/TrEMBL

A0A178UXN4, A0A5S9XYW3

Conserved Domains (1) summary

cd14066
Location:92 → 368

STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
NM_001203999.1 → NP_001190928.1 Protein kinase superfamily protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001190928.1

Status: REVIEWED

UniProtKB/TrEMBL

F4JN38

Conserved Domains (2) summary

smart00221
Location:90 → 366

STYKc; Protein kinase; unclassified specificity

cd14066
Location:93 → 369

STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs