LAP5 Chalcone and stilbene synthase family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: LAP5
Official Full Name: Chalcone and stilbene synthase family protein
Primary source: TAIR:AT4G34850
Locus tag: AT4G34850
See related: Araport:AT4G34850
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F11I11.90; F11I11_90; LESS ADHESIVE POLLEN 5; polyketide synthase B; PSKB
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Genomic context

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See LAP5 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 2

Sequence:: Chromosome: 4; NC_003075.7 (16608204..16609829)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

AT4G34850 interacts and constitutes a part of metabolon localized to the endoplasmic reticulum of tapetum cells.AT4G34850 is sporopollenin biosynthetic enzyme.
Title: Sporopollenin biosynthetic enzymes interact and constitute a metabolon localized to the endoplasmic reticulum of tapetum cells.
results show hydroxylated alpha-pyrone polyketide compounds generated by the sequential action of ACOS5 and LAP6/LAP5 are potential and previously unknown sporopollenin precursors
Title: LAP6/POLYKETIDE SYNTHASE A and LAP5/POLYKETIDE SYNTHASE B encode hydroxyalkyl α-pyrone synthases required for pollen development and sporopollenin biosynthesis in Arabidopsis thaliana.
LAP5 and LAP6 are multifunctional enzymes and may play a role in both the synthesis of pollen fatty acids and phenolics found in exine.[LAP5]
Title: LAP5 and LAP6 encode anther-specific proteins with similarity to chalcone synthase essential for pollen exine development in Arabidopsis.

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Pathways from PubChem

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General gene information

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Homology

Orthologs from OrthoDB

NM_001342307.1

Supported by ESTs:

NM_119651.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables acyltransferase activity, transferring groups other than amino-acyl groups	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables tetraketide alpha-pyrone synthase activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in flavonoid biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within pollen exine formation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within polyketide biosynthetic process	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within sporopollenin biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	ISM Inferred from Sequence Model more info
located_in endoplasmic reticulum	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: Chalcone and stilbene synthase family protein

NP_567971.1

LESS ADHESIVE POLLEN 5 (LAP5); FUNCTIONS IN: transferase activity, transferring acyl groups other than amino-acyl groups, catalytic activity, acyltransferase activity; INVOLVED IN: phenylpropanoid biosynthetic process, pollen exine formation; LOCATED IN: cellular_component unknown; EXPRESSED IN: leaf whorl, sepal, anther, flower, seed; EXPRESSED DURING: petal differentiation and expansion stage, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: Chalcone/stilbene synthase, N-terminal (InterPro:IPR001099), Thiolase-like (InterPro:IPR016039), Polyketide synthase, type III (InterPro:IPR011141), Thiolase-like, subgroup (InterPro:IPR016038), Chalcone/stilbene synthase, C-terminal (InterPro:IPR012328); BEST Arabidopsis thaliana protein match is: Chalcone and stilbene synthase family protein (TAIR:AT1G02050.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

16608204..16609829

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_119651.4 → NP_567971.1 Chalcone and stilbene synthase family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_567971.1

Status: REVIEWED

UniProtKB/Swiss-Prot

A0MFB8, Q8LDM2, Q9SW49

UniProtKB/TrEMBL

A0A178UTW2, A0A5S9XYP3, Q460T8, Q460U2, Q460V0, Q460V1, Q460V5

Conserved Domains (1) summary

PLN03169
Location:1 → 392

PLN03169; chalcone synthase family protein; Provisional
NM_001342307.1 → NP_001328609.1 Chalcone and stilbene synthase family protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8B585, Q460T8, Q460V0