DCAF1 DDB1-CUL4 associated factor 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: DCAF1
Official Full Name: DDB1-CUL4 associated factor 1
Primary source: TAIR:AT4G31160
Locus tag: AT4G31160
See related: Araport:AT4G31160
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: DDB1-CUL4 associated factor 1; F6E21.80; F6E21_80
Summary: Encodes a DCAF/DWD protein capable of interacting with DDB1 and associating with CUL4, likely as part of a nuclear ubiquitin ligase complex. DCAF1 appears to be required for plant embryogenesis and to affect several other developmental processes including leaf, shoot, and flower development.
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Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_119266.7

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within embryo development ending in seed dormancy	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within flower development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within fruit development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within leaf development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within phyllome development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein ubiquitination	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within shoot system development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of Cul4-RING E3 ubiquitin ligase complex	IPI Inferred from Physical Interaction more info	PubMed
located_in cytoplasm	ISM Inferred from Sequence Model more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed

NP_194845.4

DDB1-CUL4 associated factor 1 (DCAF1); FUNCTIONS IN: nucleotide binding; INVOLVED IN: in 6 processes; LOCATED IN: nucleus, CUL4 RING ubiquitin ligase complex; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat-like-containing domain (InterPro:IPR011046), LisH dimerisation motif, subgroup (InterPro:IPR013720), WD40-repeat-containing domain (InterPro:IPR017986), WD40 repeat (InterPro:IPR001680), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), LisH dimerisation motif (InterPro:IPR006594); Has 5754 Blast hits to 3482 proteins in 410 species: Archae - 46; Bacteria - 1277; Metazoa - 1225; Fungi - 769; Plants - 278; Viruses - 87; Other Eukaryotes - 2072 (source: NCBI BLink).

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The following sections contain reference sequences that belong to a specific genome build. Explain