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CKX4 cytokinin oxidase 4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 829096, updated on 18-Sep-2024

Summary

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Official Symbol
CKX4
Official Full Name
cytokinin oxidase 4
Primary source
TAIR:AT4G29740
Locus tag
AT4G29740
See related
Araport:AT4G29740
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATCKX4; cytokinin oxidase 4; T16L4.250; T16L4_250
Summary
It encodes a protein whose sequence is similar to cytokinin oxidase/dehydrogenase, which catalyzes the degradation of cytokinins.
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Genomic context

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See CKX4 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
5
Sequence:
Chromosome: 4; NC_003075.7 (14566183..14569380)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene nucleosome/chromatin assembly factor group C5 Neighboring gene uncharacterized protein Neighboring gene CRS1 / YhbY (CRM) domain-containing protein Neighboring gene ncRNA Neighboring gene target of trans acting-siR480/255 protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular and biochemical characterization of a cytokinin oxidase from maize. Bilyeu KD, et al. Plant Physiol, 2001 Jan. PMID 11154345, Free PMC Article
  2. Cytokinin-deficient transgenic Arabidopsis plants show multiple developmental alterations indicating opposite functions of cytokinins in the regulation of shoot and root meristem activity. Werner T, et al. Plant Cell, 2003 Nov. PMID 14555694, Free PMC Article
  3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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NM_001341977.1
NM_119120.2
NM_179139.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables FAD binding IEA
Inferred from Electronic Annotation
more info
  
enables cytokinin dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
enables cytokinin dehydrogenase activity TAS
Traceable Author Statement
more info
 PubMed 
enables primary methylamine oxidase activity TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cytokinin catabolic process TAS
Traceable Author Statement
more info
 PubMed 
involved_in cytokinin metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
cytokinin oxidase 4
NP_194703.1
  • cytokinin oxidase 4 (CKX4); FUNCTIONS IN: primary amine oxidase activity, cytokinin dehydrogenase activity; INVOLVED IN: cytokinin catabolic process; LOCATED IN: endomembrane system; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Cytokinin dehydrogenase 1, FAD/cytokinin binding domain (InterPro:IPR015345), FAD-binding, type 2 (InterPro:IPR016166), FAD-linked oxidase-like, C-terminal (InterPro:IPR016164), FAD linked oxidase, N-terminal (InterPro:IPR006094); BEST Arabidopsis thaliana protein match is: cytokinin oxidase 2 (TAIR:AT2G19500.1); Has 4206 Blast hits to 4200 proteins in 818 species: Archae - 66; Bacteria - 2585; Metazoa - 17; Fungi - 1008; Plants - 323; Viruses - 0; Other Eukaryotes - 207 (source: NCBI BLink).
NP_849470.1
  • cytokinin oxidase 4 (CKX4); FUNCTIONS IN: primary amine oxidase activity, cytokinin dehydrogenase activity; INVOLVED IN: cytokinin catabolic process; LOCATED IN: endomembrane system; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Cytokinin dehydrogenase 1, FAD/cytokinin binding domain (InterPro:IPR015345), FAD-binding, type 2 (InterPro:IPR016166), FAD-linked oxidase-like, C-terminal (InterPro:IPR016164), FAD linked oxidase, N-terminal (InterPro:IPR006094); BEST Arabidopsis thaliana protein match is: cytokinin oxidase 2 (TAIR:AT2G19500.1); Has 4201 Blast hits to 4198 proteins in 819 species: Archae - 66; Bacteria - 2589; Metazoa - 17; Fungi - 1008; Plants - 315; Viruses - 0; Other Eukaryotes - 206 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    14566183..14569380
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_119120.2 → NP_194703.1  cytokinin oxidase 4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_194703.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9FUJ2, Q9SU77
    UniProtKB/TrEMBL
    A0A178UYT5, A0A5S9XX24
    Conserved Domains (1) summary
    PLN02441
    Location:3 → 524
    PLN02441; cytokinin dehydrogenase

  2. NM_001341977.1 → NP_001328306.1  cytokinin oxidase 4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B473

  3. NM_179139.1 → NP_849470.1  cytokinin oxidase 4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_849470.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UYT5, A0A5S9XX24, F4JNR1
    Conserved Domains (2) summary
    pfam01565
    Location:64 → 218
    FAD_binding_4; FAD binding domain
    pfam09265
    Location:250 → 428
    Cytokin-bind; Cytokinin dehydrogenase 1, FAD and cytokinin binding
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9FUJ2.2

Gene LinkOut

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