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WD repeat and SOF domain-containing protein 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 828962, updated on 18-Sep-2024

Summary

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Official Full Name
WD repeat and SOF domain-containing protein 1
Primary source
TAIR:AT4G28450
Locus tag
AT4G28450
See related
Araport:AT4G28450
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F20O9.130; F20O9_130
Summary
This gene is predicted to encode a protein with a DWD motif. It can bind to DDB1a in Y2H assays and may be involved in the formation of a CUL4-based E3 ubiquitin ligase
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Genomic context

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Location:
chromosome: 4
Exon count:
16
Sequence:
Chromosome: 4; NC_003075.7 (14061403..14064708, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Reticulon family protein Neighboring gene Nucleic acid-binding, OB-fold-like protein Neighboring gene uncharacterized protein Neighboring gene 26S proteasome regulatory subunit S2 1B

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of Arabidopsis and rice DWD proteins and their roles as substrate receptors for CUL4-RING E3 ubiquitin ligases. Lee JH, et al. Plant Cell, 2008 Jan. PMID 18223036, Free PMC Article
  2. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
  3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_118987.8

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of Cul4-RING E3 ubiquitin ligase complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
WD repeat and SOF domain-containing protein 1
NP_567810.5
  • nucleotide binding;protein binding; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), Sof1-like protein (InterPro:IPR007287), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT4G02730.1); Has 37337 Blast hits to 21127 proteins in 676 species: Archae - 38; Bacteria - 5948; Metazoa - 14528; Fungi - 7710; Plants - 4379; Viruses - 0; Other Eukaryotes - 4734 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    14061403..14064708 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_118987.8 → NP_567810.5  WD repeat and SOF domain-containing protein 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_567810.5

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UZJ7, A0A5S9XWN6, A0A654FTN4, Q8W4D9, Q93VK1
    Conserved Domains (3) summary
    cd00200
    Location:63 → 360
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:69 → 107
    7WD40; WD40 repeat [structural motif]
    pfam04158
    Location:361 → 447
    Sof1; Sof1-like domain
Nucleotide Protein
Heading Accession and Version

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