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CRF4 cytokinin response factor 4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 828908, updated on 18-Sep-2024

Summary

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Official Symbol
CRF4
Official Full Name
cytokinin response factor 4
Primary source
TAIR:AT4G27950
Locus tag
AT4G27950
See related
Araport:AT4G27950
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
cytokinin response factor 4; T13J8.60; T13J8_60
Summary
encodes a member of the ERF (ethylene response factor) subfamily B-5 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 7 members in this subfamily.
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Genomic context

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See CRF4 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
1
Sequence:
Chromosome: 4; NC_003075.7 (13909542..13910995, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene PYR1-like 10 Neighboring gene manganese tracking factor for mitochondrial SOD2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ubiquitin conjugating enzyme 9

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cytokinin response factor 4 (CRF4) is induced by cold and involved in freezing tolerance. Zwack PJ, et al. Plant Cell Rep, 2016 Mar. PMID 26650835
  2. A subset of Arabidopsis AP2 transcription factors mediates cytokinin responses in concert with a two-component pathway. Rashotte AM, et al. Proc Natl Acad Sci U S A, 2006 Jul 18. PMID 16832061, Free PMC Article
  3. CRFs form protein-protein interactions with each other and with members of the cytokinin signalling pathway in Arabidopsis via the CRF domain. Cutcliffe JW, et al. J Exp Bot, 2011 Oct. PMID 21705390, Free PMC Article
  4. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Riechmann JL, et al. Science, 2000 Dec 15. PMID 11118137
  5. CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. Wanamaker SA, et al. Nat Methods, 2017 Aug. PMID 28650476, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data indicate that mutants lacking expression of cytokinin response factor 4 (CRF4) were more sensitive to freezing.
    Title: Cytokinin response factor 4 (CRF4) is induced by cold and involved in freezing tolerance.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_118933.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within leaf development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
cytokinin response factor 4
NP_194524.2
  • cytokinin response factor 4 (CRF4); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: cytokinin response factor 3 (TAIR:AT5G53290.1); Has 6110 Blast hits to 5757 proteins in 250 species: Archae - 0; Bacteria - 2; Metazoa - 0; Fungi - 2; Plants - 6087; Viruses - 2; Other Eukaryotes - 17 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    13909542..13910995 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_118933.3 → NP_194524.2  cytokinin response factor 4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_194524.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B3LFA0, Q9SUE3
    UniProtKB/TrEMBL
    A0A178V2V5, A0A5S9XYN5, A0A654FTH7
    Conserved Domains (1) summary
    smart00380
    Location:117 → 180
    AP2; DNA-binding domain in plant proteins such as APETALA2 and EREBPs
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SUE3.2

Gene LinkOut

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