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SPFH/Band 7/PHB domain-containing membrane-associated protein family [ Arabidopsis thaliana (thale cress) ]

Gene ID: 828868, updated on 18-Sep-2024

Summary

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Official Full Name
SPFH/Band 7/PHB domain-containing membrane-associated protein family
Primary source
TAIR:AT4G27585
Locus tag
AT4G27585
See related
Araport:AT4G27585
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtSLP1; SLP1; stomatin-like protein 1
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Genomic context

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Location:
chromosome: 4
Exon count:
9
Sequence:
Chromosome: 4; NC_003075.7 (13766699..13769961, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene UDP-Glycosyltransferase superfamily protein Neighboring gene phosphatidylinositol transfer SFH5-like protein Neighboring gene Heavy metal transport/detoxification superfamily protein Neighboring gene WEB family protein (DUF827) Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An Arabidopsis stomatin-like protein affects mitochondrial respiratory supercomplex organization. Gehl B, et al. Plant Physiol, 2014 Mar. PMID 24424325, Free PMC Article
  2. Heterogeneity of the mitochondrial proteome for photosynthetic and non-photosynthetic Arabidopsis metabolism. Lee CP, et al. Mol Cell Proteomics, 2008 Jul. PMID 18385124
  3. Analysis of the Arabidopsis mitochondrial proteome. Millar AH, et al. Plant Physiol, 2001 Dec. PMID 11743115, Free PMC Article
  4. Divalent metal ions in plant mitochondria and their role in interactions with proteins and oxidative stress-induced damage to respiratory function. Tan YF, et al. Plant Physiol, 2010 Feb. PMID 20018591, Free PMC Article
  5. Uncovering Arabidopsis membrane protein interactome enriched in transporters using mating-based split ubiquitin assays and classification models. Chen J, et al. Front Plant Sci, 2012. PMID 22737156, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. These findings point to a role for SLP1 in the organization of respiratory supercomplexes in Arabidopsis.[SLP1]
    Title: An Arabidopsis stomatin-like protein affects mitochondrial respiratory supercomplex organization.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_118894.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables zinc ion binding HDA PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within mitochondrial respirasome assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
SPFH/Band 7/PHB domain-containing membrane-associated protein family
NP_567778.1
  • SPFH/Band 7/PHB domain-containing membrane-associated protein family; FUNCTIONS IN: zinc ion binding; INVOLVED IN: biological_process unknown; LOCATED IN: mitochondrion, membrane; EXPRESSED IN: callus, leaf; CONTAINS InterPro DOMAIN/s: Band 7 protein (InterPro:IPR001107); BEST Arabidopsis thaliana protein match is: SPFH/Band 7/PHB domain-containing membrane-associated protein family (TAIR:AT5G54100.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    13766699..13769961 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_118894.3 → NP_567778.1  SPFH/Band 7/PHB domain-containing membrane-associated protein family [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_567778.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UVT3, A0A654FTD4, Q93VP9
    Conserved Domains (2) summary
    COG0330
    Location:62 → 330
    HflC; Regulator of protease activity HflC, stomatin/prohibitin superfamily [Posttranslational modification, protein turnover, chaperones]
    cd08829
    Location:99 → 208
    SPFH_paraslipin; Paraslipin or slipin-2 (SLP-2, a subgroup of the stomatin-like proteins (slipins) family; belonging to the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
Nucleotide Protein
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