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transcription coactivator [ Arabidopsis thaliana (thale cress) ]

Gene ID: 828135, updated on 18-Sep-2024

Summary

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Official Full Name
transcription coactivator
Primary source
TAIR:AT4G02110
Locus tag
AT4G02110
See related
Araport:AT4G02110
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
T10M13.12; T10M13_12
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Genomic context

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Location:
chromosome: 4
Exon count:
10
Sequence:
Chromosome: 4; NC_003075.7 (935006..940328)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene multidrug resistance protein ABC transporter family protein Neighboring gene Heat shock protein DnaJ with tetratricopeptide repeat-containing protein Neighboring gene CTP synthase family protein Neighboring gene galacturonosyltransferase 6 Neighboring gene uncharacterized protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The multi-BRCT domain protein DDRM2 promotes the recruitment of RAD51 to DNA damage sites to facilitate homologous recombination. Yu C, et al. New Phytol, 2023 May. PMID 36727295
  2. Analysis of BRCT5 domain-containing proteins reveals a new component of DNA damage repair in Arabidopsis. Vladejić J, et al. Front Plant Sci, 2022. PMID 36578335, Free PMC Article
  3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The multi-BRCT domain protein DDRM2 promotes the recruitment of RAD51 to DNA damage sites to facilitate homologous recombination.
    Title: The multi-BRCT domain protein DDRM2 promotes the recruitment of RAD51 to DNA damage sites to facilitate homologous recombination.
Submit: New GeneRIF Correction

General gene information

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Homology

NM_001340361.1
NM_116443.6

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage response IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within DNA damage response IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in double-strand break repair via homologous recombination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
transcription coactivator
NP_192120.4
  • transcription coactivators; FUNCTIONS IN: transcription coactivator activity; INVOLVED IN: biological_process unknown; LOCATED IN: intracellular; CONTAINS InterPro DOMAIN/s: BRCT (InterPro:IPR001357); BEST Arabidopsis thaliana protein match is: zinc finger (C3HC4-type RING finger) family protein / BRCT domain-containing protein (TAIR:AT1G67180.1); Has 6090 Blast hits to 4661 proteins in 497 species: Archae - 12; Bacteria - 945; Metazoa - 2581; Fungi - 684; Plants - 424; Viruses - 13; Other Eukaryotes - 1431 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    935006..940328
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_116443.6 → NP_192120.4  transcription coactivator [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_192120.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F4JH81, O04251
    UniProtKB/TrEMBL
    A0A178V4A1, A0A5S9XQY2, A0A654FL36
    Conserved Domains (5) summary
    COG5271
    Location:729 → 1053
    MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
    cd17711
    Location:14 → 91
    BRCT_PAXIP1_rpt3; third BRCT domain of PAX-interacting protein 1 (PAXIP1) and similar proteins
    cd17730
    Location:112 → 186
    BRCT_PAXIP1_rpt4; fourth BRCT domain of PAX-interacting protein 1 (PAXIP1) and similar proteins
    cd17738
    Location:1097 → 1171
    BRCT_TopBP1_rpt7; seventh BRCT domain of DNA topoisomerase 2-binding protein 1
    cl00038
    Location:1229 → 1295
    BRCT; C-terminal domain of the breast cancer suppressor protein (BRCA1) and related domains

  2. NM_001340361.1 → NP_001327947.1  transcription coactivator [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178V4A1, A0A1P8B350
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O04251.3

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