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TPP2 tripeptidyl peptidase ii [ Arabidopsis thaliana (thale cress) ]

Gene ID: 827833, updated on 18-Sep-2024

Summary

Official Symbol
TPP2
Official Full Name
tripeptidyl peptidase ii
Primary source
TAIR:AT4G20850
Locus tag
AT4G20850
See related
Araport:AT4G20850
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
T13K14.10; T13K14_10; tripeptidyl peptidase ii
Summary
Tripeptidyl Peptidase II. Ser protease that assembles into a large oligomeric complex containing two proteins of 153 and 142 kD that are derived from a single TPP2 gene, with the smaller version missing part of the C-terminal end. Not essential, based on the lack of phenotype of a T-DNA disruption mutant.
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Genomic context

See TPP2 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
34
Sequence:
Chromosome: 4; NC_003075.7 (11160721..11170071, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene FAD-binding Berberine family protein Neighboring gene uncharacterized protein Neighboring gene FAD-binding Berberine family protein Neighboring gene FAD-binding Berberine family protein Neighboring gene fatty acid hydroxylase 2 Neighboring gene miscRNA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
tripeptidyl peptidase ii
NP_193817.2
  • tripeptidyl peptidase ii (TPP2); FUNCTIONS IN: tripeptidyl-peptidase activity; INVOLVED IN: proteolysis; LOCATED IN: in 6 components; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase S8/S53, subtilisin/kexin/sedolisin (InterPro:IPR000209), Peptidase S8, subtilisin-related (InterPro:IPR015500), Peptidase S8/S53, subtilisin, active site (InterPro:IPR022398), Peptidase S8A, tripeptidyl peptidase II (InterPro:IPR022229); Has 6394 Blast hits to 6195 proteins in 1270 species: Archae - 226; Bacteria - 4362; Metazoa - 666; Fungi - 272; Plants - 126; Viruses - 0; Other Eukaryotes - 742 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    11160721..11170071 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_118203.4NP_193817.2  tripeptidyl peptidase ii [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_193817.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F4JVN6, Q8L640, Q9SUC7
    UniProtKB/TrEMBL
    A0A178UVT6, A0A654FR75
    Conserved Domains (2) summary
    cd04857
    Location:116598
    Peptidases_S8_Tripeptidyl_Aminopeptidase_II; Peptidase S8 family domain in Tripeptidyl aminopeptidases_II
    pfam12580
    Location:8971080
    TPPII; Tripeptidyl peptidase II