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DNA (cytosine-5-)-methyltransferase family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 826477, updated on 14-Nov-2024

Summary

Official Full Name
DNA (cytosine-5-)-methyltransferase family protein
Primary source
TAIR:AT4G08990
Locus tag
AT4G08990
See related
Araport:AT4G08990
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F23J3.20; F23J3_20
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Genomic context

Location:
chromosome: 4
Exon count:
11
Sequence:
Chromosome: 4; NC_003075.7 (5764781..5770496)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene F-BOX WITH WD-40 2 Neighboring gene miscRNA Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene general regulatory factor 1

General gene information

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA (cytosine-5-)-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in DNA methylation-dependent constitutive heterochromatin formation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
 

General protein information

Preferred Names
DNA (cytosine-5-)-methyltransferase family protein
NP_192638.1
  • DNA (cytosine-5-)-methyltransferase family protein; FUNCTIONS IN: DNA binding, DNA (cytosine-5-)-methyltransferase activity; INVOLVED IN: DNA methylation; LOCATED IN: nucleus; CONTAINS InterPro DOMAIN/s: DNA (cytosine-5)-methyltransferase 1 (InterPro:IPR017198), DNA methylase, C-5 cytosine-specific (InterPro:IPR001525), Bromo adjacent homology (BAH) domain (InterPro:IPR001025), DNA methylase, C-5 cytosine-specific, active site (InterPro:IPR018117); BEST Arabidopsis thaliana protein match is: DNA methyltransferase 2 (TAIR:AT4G14140.1); Has 7214 Blast hits to 6137 proteins in 1440 species: Archae - 249; Bacteria - 4362; Metazoa - 525; Fungi - 274; Plants - 335; Viruses - 111; Other Eukaryotes - 1358 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    5764781..5770496
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_116968.1NP_192638.1  DNA (cytosine-5-)-methyltransferase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_192638.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9M0S8
    UniProtKB/TrEMBL
    A0A178UZB7, A0A5S9XRF0
    Conserved Domains (4) summary
    cd04708
    Location:8791083
    BAH_plantDCM_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases (DCM) from plants. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG dinucleotide, has profound effects ...
    cd04712
    Location:704842
    BAH_DCM_I; BAH, or Bromo Adjacent Homology domain, as present in DNA (Cytosine-5)-methyltransferases (DCM) 1. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG dinucleotide, has profound effects on the genome. ...
    pfam12047
    Location:365516
    DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain
    cl17173
    Location:10711500
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...