FUR1 Major facilitator superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: FUR1
Official Full Name: Major facilitator superfamily protein
Primary source: TAIR:AT4G05120
Locus tag: AT4G05120
See related: Araport:AT4G05120
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATENT3; C17L7.40; C17L7_40; ENT3; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 3; FUDR RESISTANT 1
Summary: Encodes an equilibrative nucleoside transporter AtENT3. Mutations of this locus allow mutants to grow on uridine analogue fluorouridine.
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Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

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Limitation of Cytokinin Export to the Shoots by Nucleoside Transporter ENT3 and its Linkage with Root Elongation in Arabidopsis.
Title: Limitation of Cytokinin Export to the Shoots by Nucleoside Transporter ENT3 and its Linkage with Root Elongation in Arabidopsis.
a role for ENT3, which is expressed mainly in the vasculature of roots and leaves, as a major import route for nucleosides was supported.
Title: Nucleoside transport across the plasma membrane mediated by equilibrative nucleoside transporter 3 influences metabolism of Arabidopsis seedlings.
These results indicate that ENT3 is an important pyrimidine nucleoside transporter in Arabidopsis.
Title: The fluorouridine insensitive 1 (fur1) mutant is defective in equilibrative nucleoside transporter 3 (ENT3), and thus represents an important pyrimidine nucleoside uptake system in Arabidopsis thaliana.
AtENT3, but not AtENTs 1 and 6, is the main transporter for uridine uptake in Arabidopsis roots.
Title: Identification of AtENT3 as the main transporter for uridine uptake in Arabidopsis roots.

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NM_001340534.1

NM_116751.4

Function	Evidence Code	Pubs
enables nucleoside transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables nucleoside transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in nucleoside transmembrane transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within nucleoside transport	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within pyrimidine nucleoside transport	IMP Inferred from Mutant Phenotype more info

NP_192421.1

FUDR RESISTANT 1 (FUR1); FUNCTIONS IN: nucleoside transmembrane transporter activity; INVOLVED IN: nucleoside transport, pyrimidine nucleoside transport; LOCATED IN: plasma membrane; CONTAINS InterPro DOMAIN/s: Delayed-early response protein/equilibrative nucleoside transporter (InterPro:IPR002259), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: equilibrative nucleoside transporter 6 (TAIR:AT4G05110.1); Has 945 Blast hits to 913 proteins in 187 species: Archae - 0; Bacteria - 2; Metazoa - 416; Fungi - 101; Plants - 211; Viruses - 0; Other Eukaryotes - 215 (source: NCBI BLink).

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The following sections contain reference sequences that belong to a specific genome build. Explain