HWS Galactose oxidase/kelch repeat superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: HWS
Official Full Name: Galactose oxidase/kelch repeat superfamily protein
Primary source: TAIR:AT3G61590
Locus tag: AT3G61590
See related: Araport:AT3G61590
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F15G16.3; HAWAIIAN SKIRT; HS
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Genomic context

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See HWS in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 2

Sequence:: Chromosome: 3; NC_003074.8 (22791898..22794710)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HWS is a novel, F-box dependent factor involved in miRNA function
Title: A Role for the F-Box Protein HAWAIIAN SKIRT in Plant microRNA Function.
In agreement with these data, accumulation of miRNA is modified in HWS loss or gain of function mutants. Our data propose HWS as a new player in the miRNA pathway, important for plant growth.
Title: The Arabidopsis thaliana F-box gene HAWAIIAN SKIRT is a new player in the microRNA pathway.
Study demonstrated that HWS contributes to the co-ordination of floral organ number and boundary formation by altering MIR164 and CUC1 transcript levels; showed that the regulatory domain of MIR164 is crucial for this event to take place. HWS and CUC1 also regulate cell number and size in petals, and influence cell proliferation.
Title: HAWAIIAN SKIRT controls size and floral organ number by modulating CUC1 and CUC2 expression.
HWS affects quiescent center (QC)-independent transit-amplifying (TA) cell activities through a pathway distinctive from PHABULOSA (PHB).
Title: HAWAIIAN SKIRT regulates the quiescent center-independent meristem activity in Arabidopsis roots.
Results indicate that HWS affects quiescent center-independent TA(transit-amplifying) cell activities through a pathway distinctive from PHABULOSA. [HWS]
Title: HAWAIIAN SKIRT regulates the quiescent center-independent meristem activity in Arabidopsis roots.
important role in regulating plant growth and development, expression restricted to the stele and lateral root cap, cotyledonary margins, tip of the stigma, pollen, abscission zones, and developing seeds
Title: Hawaiian skirt: an F-box gene that regulates organ fusion and growth in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001340113.1

Supported by ESTs:

NM_116024.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables ubiquitin-protein transferase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within miRNA-mediated post-transcriptional gene silencing	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within plant organ development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein ubiquitination	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of SCF ubiquitin ligase complex	IPI Inferred from Physical Interaction more info	PubMed
located_in extracellular region	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: Galactose oxidase/kelch repeat superfamily protein

NP_001319816.1

HAWAIIAN SKIRT (HWS); FUNCTIONS IN: ubiquitin-protein ligase activity; INVOLVED IN: organ development; LOCATED IN: cellular_component unknown; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: F-box domain, cyclin-like (InterPro:IPR001810), F-box domain, Skp2-like (InterPro:IPR022364), Galactose oxidase/kelch, beta-propeller (InterPro:IPR011043), F-box associated interaction domain (InterPro:IPR017451); BEST Arabidopsis thaliana protein match is: Galactose oxidase/kelch repeat superfamily protein (TAIR:AT5G15710.1).

NP_191718.1

HAWAIIAN SKIRT (HWS); CONTAINS InterPro DOMAIN/s: F-box domain, cyclin-like (InterPro:IPR001810), F-box domain, Skp2-like (InterPro:IPR022364), Galactose oxidase/kelch, beta-propeller (InterPro:IPR011043), F-box associated interaction domain (InterPro:IPR017451); BEST Arabidopsis thaliana protein match is: Galactose oxidase/kelch repeat superfamily protein (TAIR:AT5G15710.1); Has 852 Blast hits to 850 proteins in 55 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 852; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

22791898..22794710

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001340111.1 → NP_001319816.1 Galactose oxidase/kelch repeat superfamily protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1I9LRL3, A0A5S9XMS6

Conserved Domains (1) summary

pfam12937
Location:49 → 87

F-box-like
NM_001340112.1 → NP_001327207.1 Galactose oxidase/kelch repeat superfamily protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1I9LRL3, A0A5S9XMS6

Conserved Domains (1) summary

pfam12937
Location:49 → 87

F-box-like
NM_116024.3 → NP_191718.1 Galactose oxidase/kelch repeat superfamily protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_191718.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9M310

UniProtKB/TrEMBL

A0A178VER1, A0A5S9XMS6

Conserved Domains (1) summary

pfam12937
Location:41 → 79

F-box-like
NM_001340113.1 → NP_001327208.1 Galactose oxidase/kelch repeat superfamily protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1I9LRL4, A0A5S9XMS6