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PRN pirin [ Arabidopsis thaliana (thale cress) ]

Gene ID: 825091, updated on 18-Sep-2024

Summary

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Official Symbol
PRN
Official Full Name
pirin
Primary source
TAIR:AT3G59220
Locus tag
AT3G59220
See related
Araport:AT3G59220
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATPIRIN1; pirin; PRN1
Summary
encodes a cupin-domain containing protein that is similar to pirins which interact with a CCAAT box binding transcription factor. The protein interacts with GPA1 (G protein alpha-subunit) in vitro. Mutants in the gene are affected in germination and early seedling development.
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Genomic context

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See PRN in Genome Data Viewer
Location:
chromosome: 3
Exon count:
6
Sequence:
Chromosome: 3; NC_003074.8 (21893812..21895789)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene F-box/RNI-like superfamily protein Neighboring gene F-box/RNI-like superfamily protein Neighboring gene RNI-like superfamily protein Neighboring gene RNI-like superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pirin1 (PRN1) is a multifunctional protein that regulates quercetin, and impacts specific light and UV responses in the seed-to-seedling transition of Arabidopsis thaliana. Orozco-Nunnelly DA, et al. PLoS One, 2014. PMID 24705271, Free PMC Article
  2. Susceptibility of intact germinating Arabidopsis thaliana to human fungal pathogens Cryptococcus neoformans and C. gattii. Warpeha KM, et al. Appl Environ Microbiol, 2013 May. PMID 23435895, Free PMC Article
  3. The Arabidopsis cupin domain protein AtPirin1 interacts with the G protein alpha-subunit GPA1 and regulates seed germination and early seedling development. Lapik YR, et al. Plant Cell, 2003 Jul. PMID 12837948, Free PMC Article
  4. The GCR1, GPA1, PRN1, NF-Y signal chain mediates both blue light and abscisic acid responses in Arabidopsis. Warpeha KM, et al. Plant Physiol, 2007 Apr. PMID 17322342, Free PMC Article
  5. Proteomic profiling of tandem affinity purified 14-3-3 protein complexes in Arabidopsis thaliana. Chang IF, et al. Proteomics, 2009 Jun. PMID 19452453, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. PRN1 may play a critical role in cellular quercetin levels and influence light- or hormonal-directed early development.
    Title: Pirin1 (PRN1) is a multifunctional protein that regulates quercetin, and impacts specific light and UV responses in the seed-to-seedling transition of Arabidopsis thaliana.
  2. Arabidopsis mutants of the PRN1 gene, which is involved in abiotic and biotic signaling affecting phenylalanine-derived flavonoids, showed altered susceptibility to cryptoccocal infections, suggesting roles for this pathway in cryptococcal defense.
    Title: Susceptibility of intact germinating Arabidopsis thaliana to human fungal pathogens Cryptococcus neoformans and C. gattii.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_115784.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in abscisic acid-activated signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in blue light signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to abscisic acid IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to low fluence blue light stimulus by blue low-fluence system NAS
Non-traceable Author Statement
more info
  
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
pirin
NP_191481.1
  • pirin (PRN); CONTAINS InterPro DOMAIN/s: Pirin, C-terminal (InterPro:IPR008778), Pirin (InterPro:IPR012093), Cupin, RmlC-type (InterPro:IPR011051), Pirin, N-terminal (InterPro:IPR003829); BEST Arabidopsis thaliana protein match is: RmlC-like cupins superfamily protein (TAIR:AT2G43120.1); Has 7400 Blast hits to 7400 proteins in 1466 species: Archae - 64; Bacteria - 4668; Metazoa - 71; Fungi - 217; Plants - 125; Viruses - 0; Other Eukaryotes - 2255 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    21893812..21895789
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_115784.3 → NP_191481.1  pirin [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_191481.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9LX49
    UniProtKB/TrEMBL
    A0A178VHE5, A0A654FJ54, Q147N7
    Conserved Domains (1) summary
    COG1741
    Location:37 → 279
    YhaK; Redox-sensitive bicupin YhaK, pirin superfamily [General function prediction only]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LX49.1

Gene LinkOut

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