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SHP1 K-box region and MADS-box transcription factor family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 825047, updated on 18-Sep-2024

Summary

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Official Symbol
SHP1
Official Full Name
K-box region and MADS-box transcription factor family protein
Primary source
TAIR:AT3G58780
Locus tag
AT3G58780
See related
Araport:AT3G58780
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AGAMOUS-like 1; AGL1; SHATTERPROOF 1
Summary
One of two genes (SHP1 and SHP2) that are required for fruit dehiscence. The two genes control dehiscence zone differentiation and promote the lignification of adjacent cells.
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Genomic context

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See SHP1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
9
Sequence:
Chromosome: 3; NC_003074.8 (21738160..21742517)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Integrin-linked protein kinase family Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene galacturonosyltransferase 15 Neighboring gene ncRNA Neighboring gene secretion-regulating guanine nucleotide exchange factor

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. SHATTERPROOF MADS-box genes control seed dispersal in Arabidopsis. Liljegren SJ, et al. Nature, 2000 Apr 13. PMID 10783890
  2. Expression of PTEN and SHP1, investigated from tissue microarrays in pediatric acute lymphoblastic, leukemia. Gauffin F, et al. Pediatr Hematol Oncol, 2009 Jan. PMID 19206008
  3. A new role for the SHATTERPROOF genes during Arabidopsis gynoecium development. Colombo M, et al. Dev Biol, 2010 Jan 15. PMID 19900437
  4. The MADS Box Genes ABS, SHP1, and SHP2 Are Essential for the Coordination of Cell Divisions in Ovule and Seed Coat Development and for Endosperm Formation in Arabidopsis thaliana. Ehlers K, et al. PLoS One, 2016. PMID 27776173, Free PMC Article
  5. Functional analysis of MADS-box genes controlling ovule development in Arabidopsis using the ethanol-inducible alc gene-expression system. Battaglia R, et al. Mech Dev, 2006 Apr. PMID 16515858

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. LAT and phospholipase C-gamma dephosphorylation by SHP-1 inhibits natural killer cell cytototoxicity
    Title: Dephosphorylation of the adaptor LAT and phospholipase C-γ by SHP-1 inhibits natural killer cell cytotoxicity.
  2. Study identified new roles for SHP1 and SHP2: they are required for synchronized ovule maturation and subsequent fertilization/seed maturation, seed mucilage production, and have an inhibitory effect which is antagonistic to the ABS function in controlling formative divisions and cell shape of the inner integument and seed coat layers.
    Title: The MADS Box Genes ABS, SHP1, and SHP2 Are Essential for the Coordination of Cell Divisions in Ovule and Seed Coat Development and for Endosperm Formation in Arabidopsis thaliana.
  3. The stk shp1 shp2 ant quadruple mutant ovule lacks integument development as in ant single mutant.
    Title: Genetic interaction between AINTEGUMENTA (ANT) and the ovule identity genes SEEDSTICK (STK), SHATTERPROOF1 (SHP1) and SHATTERPROOF2 (SHP2).
  4. SHP1/2 and TAGL1, while distinct in molecular function, regulate similar activities via their necessity for seed dispersal in Arabidopsis and tomato, respectively.
    Title: Fleshy fruit expansion and ripening are regulated by the Tomato SHATTERPROOF gene TAGL1.
  5. The present work identifies a new function for SHP1 and SHP2 genes in promoting stigma, style and medial tissue development.
    Title: A new role for the SHATTERPROOF genes during Arabidopsis gynoecium development.
  6. SHP1 showed a low expression ALL, Childhood samples
    Title: Expression of PTEN and SHP1, investigated from tissue microarrays in pediatric acute lymphoblastic, leukemia.
  7. These experiments indicate that the ectopic co-expression of SEPALLATA3 and SHATTERPROOF1 and/or SEEDSTICK is probably not sufficient to homeotically transform vegetative tissues into carpels with ovules.
    Title: Functional analysis of MADS-box genes controlling ovule development in Arabidopsis using the ethanol-inducible alc gene-expression system.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001084842.1
NM_001203201.2
NM_001339937.1
NM_001339938.1
NM_115740.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables transcription cis-regulatory region binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within carpel development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within fruit dehiscence IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within plant ovule development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
K-box region and MADS-box transcription factor family protein
NP_001078311.1
  • SHATTERPROOF 1 (SHP1); FUNCTIONS IN: protein binding, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: fruit dehiscence, ovule development, carpel development; LOCATED IN: nucleus; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Transcription factor, MADS-box (InterPro:IPR002100), Transcription factor, K-box (InterPro:IPR002487); BEST Arabidopsis thaliana protein match is: K-box region and MADS-box transcription factor family protein (TAIR:AT2G42830.1); Has 7214 Blast hits to 7213 proteins in 918 species: Archae - 0; Bacteria - 0; Metazoa - 630; Fungi - 313; Plants - 6194; Viruses - 0; Other Eukaryotes - 77 (source: NCBI BLink).
NP_001190130.1
  • SHATTERPROOF 1 (SHP1); FUNCTIONS IN: protein binding, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: fruit dehiscence, ovule development, carpel development; LOCATED IN: nucleus; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Transcription factor, MADS-box (InterPro:IPR002100), Transcription factor, K-box (InterPro:IPR002487); BEST Arabidopsis thaliana protein match is: K-box region and MADS-box transcription factor family protein (TAIR:AT2G42830.1).
NP_191437.1
  • SHATTERPROOF 1 (SHP1); FUNCTIONS IN: protein binding, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: fruit dehiscence, ovule development, carpel development; LOCATED IN: nucleus; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Transcription factor, MADS-box (InterPro:IPR002100), Transcription factor, K-box (InterPro:IPR002487); BEST Arabidopsis thaliana protein match is: K-box region and MADS-box transcription factor family protein (TAIR:AT2G42830.1); Has 7265 Blast hits to 7263 proteins in 918 species: Archae - 0; Bacteria - 0; Metazoa - 648; Fungi - 306; Plants - 6235; Viruses - 0; Other Eukaryotes - 76 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    21738160..21742517
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_115740.3 → NP_191437.1  K-box region and MADS-box transcription factor family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_191437.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P29381
    UniProtKB/TrEMBL
    A0A178VIJ3, A0A384LNV3, A0MF34, Q5XXJ3
    Conserved Domains (2) summary
    cd00265
    Location:17 → 90
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam01486
    Location:103 → 187
    K-box; K-box region

  2. NM_001339937.1 → NP_001325709.1  K-box region and MADS-box transcription factor family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LM26, A0MF34

  3. NM_001203201.2 → NP_001190130.1  K-box region and MADS-box transcription factor family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001190130.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0MF34, F4J705
    Conserved Domains (2) summary
    cd00265
    Location:17 → 77
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam01486
    Location:126 → 210
    K-box; K-box region

  4. NM_001084842.1 → NP_001078311.1  K-box region and MADS-box transcription factor family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001078311.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0MF34, Q1PEE1
    Conserved Domains (2) summary
    cd00265
    Location:17 → 83
    MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    pfam01486
    Location:94 → 178
    K-box; K-box region

  5. NM_001339938.1 → NP_001325710.1  K-box region and MADS-box transcription factor family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1I9LM27, A0MF34
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P29381.1

Gene LinkOut

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