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CSY2 citrate synthase 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 825044, updated on 18-Sep-2024

Summary

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Official Symbol
CSY2
Official Full Name
citrate synthase 2
Primary source
TAIR:AT3G58750
Locus tag
AT3G58750
See related
Araport:AT3G58750
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
citrate synthase 2
Summary
Encodes a peroxisomal citrate synthase that is expressed throughout seedling and shoot development.
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Genomic context

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See CSY2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
12
Sequence:
Chromosome: 3; NC_003074.8 (21724306..21728137, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene vacuolar ATP synthase subunit D (VATD) / V-ATPase D subunit / vacuolar proton pump D subunit (VATPD) Neighboring gene citrate synthase 1 Neighboring gene Integrin-linked protein kinase family Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Reduced peroxisomal citrate synthase activity increases substrate availability for polyhydroxyalkanoate biosynthesis in plant peroxisomes. Tilbrook K, et al. Plant Biotechnol J, 2014 Oct. PMID 24944109
  2. Arabidopsis peroxisomal citrate synthase is required for fatty acid respiration and seed germination. Pracharoenwattana I, et al. Plant Cell, 2005 Jul. PMID 15923350, Free PMC Article
  3. Arabidopsis plasmodesmal proteome. Fernandez-Calvino L, et al. PLoS One, 2011 Apr 20. PMID 21533090, Free PMC Article
  4. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
  5. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Reduced peroxisomal citrate synthase activity in a peroxisomal polyhydroxyalkanoate (PHA)-producing Arabidopsis line increases PHA accumulation
    Title: Reduced peroxisomal citrate synthase activity increases substrate availability for polyhydroxyalkanoate biosynthesis in plant peroxisomes.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_115737.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables citrate (Si)-synthase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within fatty acid beta-oxidation IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosol HDA PubMed 
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  
located_in peroxisome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasmodesma HDA PubMed 
located_in secretory vesicle HDA PubMed 

General protein information

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Preferred Names
citrate synthase 2
NP_191434.1
  • citrate synthase 2 (CSY2); FUNCTIONS IN: citrate (SI)-synthase activity; INVOLVED IN: fatty acid beta-oxidation, tricarboxylic acid cycle; LOCATED IN: peroxisome; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Citrate synthase, type II (InterPro:IPR010953), Citrate synthase-like, large alpha subdomain (InterPro:IPR016142), Citrate synthase active site (InterPro:IPR019810), Citrate synthase-like, core (InterPro:IPR016141), Citrate synthase-like (InterPro:IPR002020); BEST Arabidopsis thaliana protein match is: citrate synthase 3 (TAIR:AT2G42790.1); Has 13448 Blast hits to 13446 proteins in 3190 species: Archae - 173; Bacteria - 8550; Metazoa - 303; Fungi - 319; Plants - 178; Viruses - 0; Other Eukaryotes - 3925 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    21724306..21728137 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_115737.3 → NP_191434.1  citrate synthase 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_191434.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q570I4, Q9LXS6
    UniProtKB/TrEMBL
    A0A178VNV2, A0A5S9XM11, A0A654FJ02
    Conserved Domains (1) summary
    PLN02456
    Location:32 → 485
    PLN02456; citrate synthase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LXS6.1

Gene LinkOut

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