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CRD1 dicarboxylate diiron protein, putative (Crd1) [ Arabidopsis thaliana (thale cress) ]

Gene ID: 824861, updated on 18-Sep-2024

Summary

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Official Symbol
CRD1
Official Full Name
dicarboxylate diiron protein, putative (Crd1)
Primary source
TAIR:AT3G56940
Locus tag
AT3G56940
See related
Araport:AT3G56940
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ACSF; CHL27; COPPER RESPONSE DEFECT 1; T8M16.1
Summary
Encodes a putative ZIP protein with varying mRNA accumulation in leaves, stems and roots. Has a consensus carboxylate-bridged di-iron binding site.
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Genomic context

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See CRD1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
5
Sequence:
Chromosome: 3; NC_003074.8 (21076505..21078443)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene DHHC-type zinc finger family protein Neighboring gene DHHC-type zinc finger family protein Neighboring gene ncRNA Neighboring gene small and basic intrinsic protein 2;1 Neighboring gene ncRNA Neighboring gene phosphatidyl inositol monophosphate 5 kinase 4 Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Role of Arabidopsis CHL27 protein for photosynthesis, chloroplast development and gene expression profiling. Bang WY, et al. Plant Cell Physiol, 2008 Sep. PMID 18682427
  2. Arabidopsis CHL27, located in both envelope and thylakoid membranes, is required for the synthesis of protochlorophyllide. Tottey S, et al. Proc Natl Acad Sci U S A, 2003 Dec 23. PMID 14673103, Free PMC Article
  3. [Identification and tissue-specific expression of a full length cDNA encoding ZIP protein in Arabidopsis]. Zheng CC, et al. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai), 2002 Jan. PMID 11958125
  4. PAPP5 is involved in the tetrapyrrole mediated plastid signalling during chloroplast development. Barajas-López Jde D, et al. PLoS One, 2013. PMID 23555952, Free PMC Article
  5. Potential roles of YCF54 and ferredoxin-NADPH reductase for magnesium protoporphyrin monomethylester cyclase. Herbst J, et al. Plant J, 2018 May. PMID 29443418

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001203183.1
NM_115553.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA binding TAS
Traceable Author Statement
more info
 PubMed 
enables mRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity IEA
Inferred from Electronic Annotation
more info
  
enables magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity NAS
Non-traceable Author Statement
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in chlorophyll biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within chlorophyll biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within chloroplast organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of tetrapyrrole metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast envelope HDA PubMed 
located_in chloroplast inner membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in chloroplast thylakoid HDA PubMed 
located_in chloroplast thylakoid membrane HDA PubMed 
located_in chloroplast thylakoid membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
dicarboxylate diiron protein, putative (Crd1)
NP_001190112.1
  • COPPER RESPONSE DEFECT 1 (CRD1); FUNCTIONS IN: magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity, DNA binding; INVOLVED IN: chlorophyll biosynthetic process, oxidation reduction, photosynthesis; LOCATED IN: chloroplast thylakoid membrane, chloroplast inner membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Magnesium-protoporphyrin IX monomethyl ester aerobic oxidative cyclase (InterPro:IPR008434), Ferritin/ribonucleotide reductase-like (InterPro:IPR009078), Rubrerythrin (InterPro:IPR003251).
NP_191253.1
  • COPPER RESPONSE DEFECT 1 (CRD1); FUNCTIONS IN: magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity, DNA binding; INVOLVED IN: chlorophyll biosynthetic process, oxidation reduction, photosynthesis; LOCATED IN: chloroplast thylakoid membrane, chloroplast, chloroplast inner membrane, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Magnesium-protoporphyrin IX monomethyl ester aerobic oxidative cyclase (InterPro:IPR008434), Ferritin/ribonucleotide reductase-like (InterPro:IPR009078), Rubrerythrin (InterPro:IPR003251); Has 877 Blast hits to 876 proteins in 230 species: Archae - 0; Bacteria - 301; Metazoa - 0; Fungi - 0; Plants - 215; Viruses - 0; Other Eukaryotes - 361 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    21076505..21078443
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_115553.4 → NP_191253.1  dicarboxylate diiron protein, putative (Crd1) [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_191253.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O04051, Q38892, Q8GUS3, Q9M1K4, Q9M591
    UniProtKB/TrEMBL
    A0A178VH55, A0A5S9XM90
    Conserved Domains (1) summary
    PLN02508
    Location:60 → 409
    PLN02508; magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase

  2. NM_001203183.1 → NP_001190112.1  dicarboxylate diiron protein, putative (Crd1) [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001190112.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4J0U9
    Conserved Domains (1) summary
    cl00264
    Location:1 → 332
    Ferritin_like; Ferritin-like superfamily of diiron-containing four-helix-bundle proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9M591.2

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