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RING/U-box superfamily protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 824825, updated on 18-Sep-2024

Summary

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Official Full Name
RING/U-box superfamily protein
Primary source
TAIR:AT3G56580
Locus tag
AT3G56580
See related
Araport:AT3G56580
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtRZF1; RING Zinc Finger 1; RZF1; T5P19.5
Summary
Encodes a functional E3 ubiquitin ligase involved in the dehydration stress response and regulation of proline biosynthesis.
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Genomic context

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Location:
chromosome: 3
Exon count:
2
Sequence:
Chromosome: 3; NC_003074.8 (20961543..20963817)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene NAC domain containing protein 65 Neighboring gene SET domain-containing protein Neighboring gene hydroxyproline-rich glycoprotein family protein Neighboring gene phosphatidylinositol 4-kinase gamma-like protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The atrzf1 mutation of the novel RING-type E3 ubiquitin ligase increases proline contents and enhances drought tolerance in Arabidopsis. Ju HW, et al. Plant Sci, 2013 Apr. PMID 23415322
  2. Rhamnogalacturonan lyase 1 (RGL1), as a suppressor of E3 ubiquitin ligase Arabidopsis thaliana ring zinc finger 1 (AtRZF1), is involved in dehydration response to mediate proline synthesis and pectin rhamnogalacturonan-I composition. Min JH, et al. Plant J, 2024 Jul. PMID 38743860
  3. Arabidopsis thaliana Ubiquitin-Associated Protein 1 (AtUAP1) Interacts with redundant RING Zinc Finger 1 (AtRZF1) to Negatively Regulate Dehydration Response. Min JH, et al. Plant Cell Physiol, 2021 Oct 11. PMID 34086919
  4. Loss of Ribosomal Protein L24A (RPL24A) suppresses proline accumulation of Arabidopsis thaliana ring zinc finger 1 (atrzf1) mutant in response to osmotic stress. Park SH, et al. Biochem Biophys Res Commun, 2017 Dec 16. PMID 29066352
  5. PCA22 acts as a suppressor of atrzf1 to mediate proline accumulation in response to abiotic stress in Arabidopsis. Kim AR, et al. J Exp Bot, 2017 Mar 1. PMID 28369480, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Rhamnogalacturonan lyase 1 (RGL1), as a suppressor of E3 ubiquitin ligase Arabidopsis thaliana ring zinc finger 1 (AtRZF1), is involved in dehydration response to mediate proline synthesis and pectin rhamnogalacturonan-I composition.
    Title: Rhamnogalacturonan lyase 1 (RGL1), as a suppressor of E3 ubiquitin ligase Arabidopsis thaliana ring zinc finger 1 (AtRZF1), is involved in dehydration response to mediate proline synthesis and pectin rhamnogalacturonan-I composition.
  2. Arabidopsis thaliana Ubiquitin-Associated Protein 1 (AtUAP1) Interacts with redundant RING Zinc Finger 1 (AtRZF1) to Negatively Regulate Dehydration Response.
    Title: Arabidopsis thaliana Ubiquitin-Associated Protein 1 (AtUAP1) Interacts with redundant RING Zinc Finger 1 (AtRZF1) to Negatively Regulate Dehydration Response.
  3. BES1/BZR1 Homolog 3 cooperates with E3 ligase AtRZF1 to regulate osmotic stress and brassinosteroid responses in Arabidopsis.
    Title: BES1/BZR1 Homolog 3 cooperates with E3 ligase AtRZF1 to regulate osmotic stress and brassinosteroid responses in Arabidopsis.
  4. Generally, pca22 mutant plants displayed suppressed atrzf1 insensitivity to dehydration and abscisic acid during early seedling growth. Additionally, the pca22 mutant exhibited shorter pollen tube length than wild-type (WT) and atrzf1 plants.
    Title: PCA22 acts as a suppressor of atrzf1 to mediate proline accumulation in response to abiotic stress in Arabidopsis.
  5. These results suggest that pca21 acts as partial suppressor of atrzf1 in the osmotic stress response through the Pro-mediated pathway.
    Title: Loss of Ribosomal Protein L24A (RPL24A) suppresses proline accumulation of Arabidopsis thaliana ring zinc finger 1 (atrzf1) mutant in response to osmotic stress.
  6. The E3 ligase AtRZF1 is an important regulator of water deficit stress during early seedling development.
    Title: The atrzf1 mutation of the novel RING-type E3 ubiquitin ligase increases proline contents and enhances drought tolerance in Arabidopsis.
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General gene information

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Homology

NM_001035797.1
NM_115516.3
NM_202719.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin-protein transferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of proline biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of response to osmotic stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to osmotic stress IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to water deprivation IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
RING/U-box superfamily protein
NP_001030874.1
  • RING/U-box superfamily protein; FUNCTIONS IN: zinc ion binding; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: RING-H2 finger C1A (TAIR:AT2G40830.3); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_567039.1
  • RING/U-box superfamily protein; FUNCTIONS IN: zinc ion binding; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: RING-H2 finger C1A (TAIR:AT2G40830.3); Has 10169 Blast hits to 10097 proteins in 280 species: Archae - 0; Bacteria - 6; Metazoa - 2759; Fungi - 920; Plants - 4864; Viruses - 13; Other Eukaryotes - 1607 (source: NCBI BLink).
NP_974448.1
  • RING/U-box superfamily protein; FUNCTIONS IN: zinc ion binding; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: RING-H2 finger C1A (TAIR:AT2G40830.3); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    20961543..20963817
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_115516.3 → NP_567039.1  RING/U-box superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_567039.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q94AK4, Q9LXY2
    UniProtKB/TrEMBL
    A0A178VB98, A0A5S9XLD8, A0A654FGX7
    Conserved Domains (2) summary
    cd16667
    Location:186 → 227
    RING-H2_RNF126_like; RING finger, H2 subclass, found in RING finger proteins RNF126, RNF115, and similar proteins
    pfam14369
    Location:6 → 37
    zinc_ribbon_9; zinc-ribbon

  2. NM_202719.1 → NP_974448.1  RING/U-box superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_974448.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q94AK4, Q9LXY2
    UniProtKB/TrEMBL
    A0A178VB98, A0A5S9XLD8, A0A654FGX7
    Conserved Domains (2) summary
    cd16667
    Location:186 → 227
    RING-H2_RNF126_like; RING finger, H2 subclass, found in RING finger proteins RNF126, RNF115, and similar proteins
    pfam14369
    Location:6 → 37
    zinc_ribbon_9; zinc-ribbon

  3. NM_001035797.1 → NP_001030874.1  RING/U-box superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001030874.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q94AK4, Q9LXY2
    UniProtKB/TrEMBL
    A0A178VB98, A0A5S9XLD8, A0A654FGX7
    Conserved Domains (2) summary
    cd16667
    Location:186 → 227
    RING-H2_RNF126_like; RING finger, H2 subclass, found in RING finger proteins RNF126, RNF115, and similar proteins
    pfam14369
    Location:6 → 37
    zinc_ribbon_9; zinc-ribbon
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q94AK4.1

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