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2-oxoglutarate dehydrogenase, E1 component [ Arabidopsis thaliana (thale cress) ]

Gene ID: 824707, updated on 18-Sep-2024

Summary

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Official Full Name
2-oxoglutarate dehydrogenase, E1 component
Primary source
TAIR:AT3G55410
Locus tag
AT3G55410
See related
Araport:AT3G55410
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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Genomic context

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Location:
chromosome: 3
Exon count:
9
Sequence:
Chromosome: 3; NC_003074.8 (20541269..20546053)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Uncharacterized protein family (UPF0497) Neighboring gene methionyl-tRNA synthetase / methionine-tRNA ligase / MetRS (cpMetRS) Neighboring gene uncharacterized protein Neighboring gene O-Glycosyl hydrolases family 17 protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Divalent metal ions in plant mitochondria and their role in interactions with proteins and oxidative stress-induced damage to respiratory function. Tan YF, et al. Plant Physiol, 2010 Feb. PMID 20018591, Free PMC Article
  2. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article
  3. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
  4. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
  5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_115399.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables cobalt ion binding HDA PubMed 
enables oxoglutarate dehydrogenase (succinyl-transferring) activity IEA
Inferred from Electronic Annotation
more info
  
enables thiamine pyrophosphate binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding HDA PubMed 
Component Evidence Code Pubs
located_in cytosol HDA PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
2-oxoglutarate dehydrogenase, E1 component
NP_191101.2
  • 2-oxoglutarate dehydrogenase, E1 component; FUNCTIONS IN: oxoglutarate dehydrogenase (succinyl-transferring) activity, cobalt ion binding, zinc ion binding; INVOLVED IN: glycolysis, metabolic process; LOCATED IN: mitochondrion; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: 2-oxoglutarate dehydrogenase, E1 component (InterPro:IPR011603), Dehydrogenase, E1 component (InterPro:IPR001017), Transketolase-like, pyrimidine-binding domain (InterPro:IPR005475); BEST Arabidopsis thaliana protein match is: 2-oxoglutarate dehydrogenase, E1 component (TAIR:AT5G65750.1); Has 10999 Blast hits to 10962 proteins in 1954 species: Archae - 31; Bacteria - 4409; Metazoa - 546; Fungi - 299; Plants - 167; Viruses - 0; Other Eukaryotes - 5547 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    20541269..20546053
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001339729.1 → NP_001327477.1  2-oxoglutarate dehydrogenase, E1 component [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178VFK1, A0A384KLZ3, F4IWV2, Q84VW8
    Conserved Domains (1) summary
    PRK09404
    Location:62 → 1012
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed

  2. NM_115399.3 → NP_191101.2  2-oxoglutarate dehydrogenase, E1 component [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_191101.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178VFK1, A0A384KLZ3, F4IWV2, Q84VW8
    Conserved Domains (1) summary
    PRK09404
    Location:62 → 1012
    sucA; 2-oxoglutarate dehydrogenase E1 component; Reviewed
Nucleotide Protein
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